2QYT

Crystal structure of 2-dehydropantoate 2-reductase from Porphyromonas gingivalis W83

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0008677	molecular_function	2-dehydropantoate 2-reductase activity
A	0015940	biological_process	pantothenate biosynthetic process
A	0016491	molecular_function	oxidoreductase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE SO4 A 315

Chain	Residue
A	GLY15
A	LYS89
A	ALA141
A	ARG142
A	LYS143
A	SO4318
A	EDO320
A	HOH443
A	HOH444

---

site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 A 316

Chain	Residue
A	LEU13
A	ALA41
A	ARG42
A	HIS45
A	LYS143
A	SO4318
A	HOH365
A	HOH393

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 317

Chain	Residue
A	ASP32
A	GLU281
A	THR282
A	GLY285
A	ARG289
A	TYR305

---

site_id	AC4
Number of Residues	10
Details	BINDING SITE FOR RESIDUE SO4 A 318

Chain	Residue
A	GLY12
A	LEU13
A	GLY14
A	CYS87
A	THR88
A	ASP90
A	SO4315
A	SO4316
A	EDO320
A	HOH443

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 319

Chain	Residue
A	TYR186
A	TYR186
A	ASN187
A	EDO324
A	EDO324
A	HOH459

---

site_id	AC6
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO A 320

Chain	Residue
A	GLY12
A	GLY14
A	GLY15
A	VAL16
A	GLY17
A	CYS87
A	SO4315
A	SO4318

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 321

Chain	Residue
A	THR80
A	GLY105
A	GLN106
A	THR130

---

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO A 322

Chain	Residue
A	ALA293
A	ARG295
A	HOH440

---

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 323

Chain	Residue
A	TYR19
A	ARG62
A	ASP154
A	GLU156
A	ARG184
A	HOH471

---

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 324

Chain	Residue
A	TYR186
A	ASN187
A	PRO188
A	TYR194
A	SO4319
A	SO4319

---