2QVH
Crystal structure of O-succinylbenzoate synthase complexed with O-succinyl benzoate (OSB)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0009063 | biological_process | amino acid catabolic process |
| A | 0009234 | biological_process | menaquinone biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016836 | molecular_function | hydro-lyase activity |
| A | 0043748 | molecular_function | O-succinylbenzoate synthase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0009063 | biological_process | amino acid catabolic process |
| B | 0009234 | biological_process | menaquinone biosynthetic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0016836 | molecular_function | hydro-lyase activity |
| B | 0043748 | molecular_function | O-succinylbenzoate synthase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 401 |
| Chain | Residue |
| A | ASP130 |
| A | GLU156 |
| A | ASP179 |
| A | OSB5550 |
| A | HOH5658 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B 400 |
| Chain | Residue |
| B | HOH5552 |
| B | ASP130 |
| B | GLU156 |
| B | ASP179 |
| B | OSB5551 |
| site_id | AC3 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE OSB A 5550 |
| Chain | Residue |
| A | PHE16 |
| A | ASN73 |
| A | THR75 |
| A | LYS97 |
| A | ASP130 |
| A | ASN132 |
| A | GLU156 |
| A | ASP179 |
| A | LYS203 |
| A | SER227 |
| A | SER228 |
| A | VAL230 |
| A | GLY254 |
| A | THR257 |
| A | MG401 |
| A | HOH5582 |
| A | HOH5583 |
| A | HOH5658 |
| site_id | AC4 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE OSB B 5551 |
| Chain | Residue |
| B | PHE16 |
| B | ASN73 |
| B | THR75 |
| B | LYS97 |
| B | ASP130 |
| B | ASN132 |
| B | GLU156 |
| B | ASP179 |
| B | ARG183 |
| B | LYS203 |
| B | SER227 |
| B | SER228 |
| B | VAL230 |
| B | GLY254 |
| B | THR257 |
| B | MG400 |
| B | HOH5578 |
| B | HOH5587 |
Functional Information from PROSITE/UniProt
| site_id | PS00909 |
| Number of Residues | 32 |
| Details | MR_MLE_2 Mandelate racemase / muconate lactonizing enzyme family signature 2. VriDvNgawdvdtAvrmirlLdrfeleyVEQP |
| Chain | Residue | Details |
| A | VAL127-PRO158 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"HAMAP-Rule","id":"MF_00470","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_00470","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24060347","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2QVH","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00470","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"24060347","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2QVH","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1r6w |
| Chain | Residue | Details |
| A | ALA101 | |
| A | LYS203 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1r6w |
| Chain | Residue | Details |
| B | ALA101 | |
| B | LYS203 |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1r6w |
| Chain | Residue | Details |
| A | LYS99 | |
| A | LYS203 |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1r6w |
| Chain | Residue | Details |
| B | LYS99 | |
| B | LYS203 |
