Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 251 A 1 |
| Chain | Residue |
| A | ASP94 |
| A | GLY96 |
| A | TYR133 |
| A | PHE170 |
| A | TRP177 |
| A | ILE180 |
| A | ARG190 |
| A | ASP290 |
| A | HOH583 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ILVDTGSSNFAV |
| Chain | Residue | Details |
| A | ILE91-VAL102 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP94 | |
| A | ASP290 | |
| Chain | Residue | Details |
| A | LYS127 | |
| A | LYS276 | |
| A | LYS280 | |
| A | LYS286 | |
| A | LYS300 | |
| A | LYS301 | |
| A | LYS308 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN154 | |
| A | ASN173 | |
| A | ASN224 | |
| A | ASN355 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | SER97 | |
| A | THR293 | |
| A | ASP290 | |
| A | ASP94 | |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | SER291 | |
| A | THR95 | |
| A | ASP290 | |
| A | ASP94 | |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | SER97 | |
| A | ASP290 | |
| A | ASP94 | |
| site_id | CSA4 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | SER97 | |
| A | TYR133 | |
| A | ASP290 | |
| A | ASP94 | |
| site_id | CSA5 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | THR95 | |
| A | THR293 | |
| A | ASP290 | |
| A | ASP94 | |
| site_id | CSA6 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | ASP94 | |
| site_id | CSA7 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | ASP290 | |
