2QTV
Structure of Sec23-Sar1 complexed with the active fragment of Sec31
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000139 | cellular_component | Golgi membrane |
| A | 0003400 | biological_process | regulation of COPII vesicle coating |
| A | 0005096 | molecular_function | GTPase activator activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005783 | cellular_component | endoplasmic reticulum |
| A | 0005789 | cellular_component | endoplasmic reticulum membrane |
| A | 0005794 | cellular_component | Golgi apparatus |
| A | 0006886 | biological_process | intracellular protein transport |
| A | 0006888 | biological_process | endoplasmic reticulum to Golgi vesicle-mediated transport |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0012507 | cellular_component | ER to Golgi transport vesicle membrane |
| A | 0015031 | biological_process | protein transport |
| A | 0016020 | cellular_component | membrane |
| A | 0016192 | biological_process | vesicle-mediated transport |
| A | 0016236 | biological_process | macroautophagy |
| A | 0030127 | cellular_component | COPII vesicle coat |
| A | 0031410 | cellular_component | cytoplasmic vesicle |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0061709 | biological_process | reticulophagy |
| A | 0070863 | biological_process | positive regulation of protein exit from endoplasmic reticulum |
| A | 0070971 | cellular_component | endoplasmic reticulum exit site |
| A | 0090110 | biological_process | COPII-coated vesicle cargo loading |
| A | 0090114 | biological_process | COPII-coated vesicle budding |
| A | 1902953 | biological_process | positive regulation of ER to Golgi vesicle-mediated transport |
| B | 0003924 | molecular_function | GTPase activity |
| B | 0005525 | molecular_function | GTP binding |
| B | 0006886 | biological_process | intracellular protein transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 800 |
| Chain | Residue |
| A | CYS56 |
| A | CYS61 |
| A | CYS80 |
| A | CYS83 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B 210 |
| Chain | Residue |
| B | THR37 |
| B | THR54 |
| B | GNP200 |
| B | HOH213 |
| B | HOH219 |
| site_id | AC3 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE GNP B 200 |
| Chain | Residue |
| A | ARG722 |
| B | ASP32 |
| B | ASN33 |
| B | ALA34 |
| B | GLY35 |
| B | LYS36 |
| B | THR37 |
| B | THR38 |
| B | PRO53 |
| B | THR54 |
| B | GLY76 |
| B | ASN132 |
| B | LYS133 |
| B | ASP135 |
| B | SER172 |
| B | VAL173 |
| B | VAL174 |
| B | MG210 |
| B | HOH213 |
| B | HOH219 |
| B | HOH222 |
| B | HOH227 |
| B | HOH238 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | BINDING: |
| Chain | Residue | Details |
| B | GLY30 | |
| B | ASP73 | |
| B | ASN132 | |
| A | CYS83 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:19779198 |
| Chain | Residue | Details |
| B | THR155 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18407956, ECO:0007744|PubMed:19779198 |
| Chain | Residue | Details |
| B | SER157 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0007744|PubMed:22106047 |
| Chain | Residue | Details |
| B | LYS133 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ksj |
| Chain | Residue | Details |
| B | HIS77 |
