2QSS
Bovine hemoglobin at pH 6.3
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004601 | molecular_function | peroxidase activity |
| A | 0005344 | molecular_function | oxygen carrier activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005833 | cellular_component | hemoglobin complex |
| A | 0015671 | biological_process | oxygen transport |
| A | 0019825 | molecular_function | oxygen binding |
| A | 0020037 | molecular_function | heme binding |
| A | 0031720 | molecular_function | haptoglobin binding |
| A | 0031838 | cellular_component | haptoglobin-hemoglobin complex |
| A | 0042744 | biological_process | hydrogen peroxide catabolic process |
| A | 0043177 | molecular_function | organic acid binding |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0098869 | biological_process | cellular oxidant detoxification |
| B | 0004601 | molecular_function | peroxidase activity |
| B | 0005344 | molecular_function | oxygen carrier activity |
| B | 0005833 | cellular_component | hemoglobin complex |
| B | 0015671 | biological_process | oxygen transport |
| B | 0019825 | molecular_function | oxygen binding |
| B | 0020037 | molecular_function | heme binding |
| B | 0031720 | molecular_function | haptoglobin binding |
| B | 0031721 | molecular_function | hemoglobin alpha binding |
| B | 0031838 | cellular_component | haptoglobin-hemoglobin complex |
| B | 0042744 | biological_process | hydrogen peroxide catabolic process |
| B | 0043177 | molecular_function | organic acid binding |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0098869 | biological_process | cellular oxidant detoxification |
| C | 0004601 | molecular_function | peroxidase activity |
| C | 0005344 | molecular_function | oxygen carrier activity |
| C | 0005506 | molecular_function | iron ion binding |
| C | 0005515 | molecular_function | protein binding |
| C | 0005833 | cellular_component | hemoglobin complex |
| C | 0015671 | biological_process | oxygen transport |
| C | 0019825 | molecular_function | oxygen binding |
| C | 0020037 | molecular_function | heme binding |
| C | 0031720 | molecular_function | haptoglobin binding |
| C | 0031838 | cellular_component | haptoglobin-hemoglobin complex |
| C | 0042744 | biological_process | hydrogen peroxide catabolic process |
| C | 0043177 | molecular_function | organic acid binding |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0098869 | biological_process | cellular oxidant detoxification |
| D | 0004601 | molecular_function | peroxidase activity |
| D | 0005344 | molecular_function | oxygen carrier activity |
| D | 0005833 | cellular_component | hemoglobin complex |
| D | 0015671 | biological_process | oxygen transport |
| D | 0019825 | molecular_function | oxygen binding |
| D | 0020037 | molecular_function | heme binding |
| D | 0031720 | molecular_function | haptoglobin binding |
| D | 0031721 | molecular_function | hemoglobin alpha binding |
| D | 0031838 | cellular_component | haptoglobin-hemoglobin complex |
| D | 0042744 | biological_process | hydrogen peroxide catabolic process |
| D | 0043177 | molecular_function | organic acid binding |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0098869 | biological_process | cellular oxidant detoxification |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CMO A 143 |
| Chain | Residue |
| A | HIS58 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE HEM A 142 |
| Chain | Residue |
| A | ASN97 |
| A | PHE98 |
| A | LEU101 |
| A | LEU136 |
| A | HOH210 |
| A | HOH274 |
| A | TYR42 |
| A | PHE43 |
| A | HIS58 |
| A | LYS61 |
| A | LEU83 |
| A | LEU86 |
| A | HIS87 |
| A | LEU91 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CMO B 147 |
| Chain | Residue |
| B | HIS62 |
| B | HIS91 |
| site_id | AC4 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE HEM B 146 |
| Chain | Residue |
| B | THR37 |
| B | PHE40 |
| B | PHE41 |
| B | HIS62 |
| B | SER69 |
| B | LEU90 |
| B | HIS91 |
| B | LEU95 |
| B | ASN101 |
| B | PHE102 |
| B | LEU105 |
| B | LEU140 |
| B | HOH186 |
| D | LYS7 |
| D | HOH210 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CMO C 143 |
| Chain | Residue |
| C | HIS58 |
| site_id | AC6 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE HEM C 142 |
| Chain | Residue |
| C | TYR42 |
| C | PHE43 |
| C | HIS45 |
| C | HIS58 |
| C | LYS61 |
| C | LEU86 |
| C | HIS87 |
| C | LEU91 |
| C | ASN97 |
| C | PHE98 |
| C | LEU101 |
| C | LEU136 |
| C | HOH190 |
| C | HOH265 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CMO D 147 |
| Chain | Residue |
| D | HIS62 |
| site_id | AC8 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE HEM D 146 |
| Chain | Residue |
| C | ALA4 |
| D | PHE40 |
| D | PHE41 |
| D | HIS62 |
| D | LYS65 |
| D | SER69 |
| D | HIS91 |
| D | LEU95 |
| D | ASN101 |
| D | LEU105 |
| D | LEU140 |
| D | HOH167 |
| D | HOH191 |
| D | HOH223 |
| D | HOH241 |
| D | HOH252 |
| D | HOH267 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | BINDING: distal binding residue |
| Chain | Residue | Details |
| B | HIS62 | |
| D | HIS62 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: proximal binding residue |
| Chain | Residue | Details |
| B | HIS91 | |
| D | HIS91 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:P68871 |
| Chain | Residue | Details |
| B | THR11 | |
| D | THR11 | |
| A | SER49 | |
| C | SER3 | |
| C | SER35 | |
| C | SER49 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P68871 |
| Chain | Residue | Details |
| B | SER43 | |
| D | SER43 | |
| A | LYS40 | |
| C | LYS7 | |
| C | LYS11 | |
| C | LYS40 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P68871 |
| Chain | Residue | Details |
| B | LYS58 | |
| B | LYS81 | |
| D | LYS58 | |
| D | LYS81 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | MOD_RES: S-nitrosocysteine => ECO:0000250|UniProtKB:P68871 |
| Chain | Residue | Details |
| B | CYS92 | |
| D | CYS92 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 6 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P01942 |
| Chain | Residue | Details |
| A | SER102 | |
| A | SER124 | |
| A | SER138 | |
| C | SER102 | |
| C | SER124 | |
| C | SER138 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 6 |
| Details | MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:P01942 |
| Chain | Residue | Details |
| A | THR108 | |
| A | THR134 | |
| A | THR137 | |
| C | THR108 | |
| C | THR134 | |
| C | THR137 |
