2QRY

Periplasmic thiamin binding protein

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0015888	biological_process	thiamine transport
A	0016020	cellular_component	membrane
A	0030288	cellular_component	outer membrane-bounded periplasmic space
A	0030975	molecular_function	thiamine binding
A	0030976	molecular_function	thiamine pyrophosphate binding
A	0042597	cellular_component	periplasmic space
A	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
A	0055085	biological_process	transmembrane transport
A	0071934	biological_process	thiamine transmembrane transport
B	0015888	biological_process	thiamine transport
B	0016020	cellular_component	membrane
B	0030288	cellular_component	outer membrane-bounded periplasmic space
B	0030975	molecular_function	thiamine binding
B	0030976	molecular_function	thiamine pyrophosphate binding
B	0042597	cellular_component	periplasmic space
B	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
B	0055085	biological_process	transmembrane transport
B	0071934	biological_process	thiamine transmembrane transport
C	0015888	biological_process	thiamine transport
C	0016020	cellular_component	membrane
C	0030288	cellular_component	outer membrane-bounded periplasmic space
C	0030975	molecular_function	thiamine binding
C	0030976	molecular_function	thiamine pyrophosphate binding
C	0042597	cellular_component	periplasmic space
C	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
C	0055085	biological_process	transmembrane transport
C	0071934	biological_process	thiamine transmembrane transport
D	0015888	biological_process	thiamine transport
D	0016020	cellular_component	membrane
D	0030288	cellular_component	outer membrane-bounded periplasmic space
D	0030975	molecular_function	thiamine binding
D	0030976	molecular_function	thiamine pyrophosphate binding
D	0042597	cellular_component	periplasmic space
D	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
D	0055085	biological_process	transmembrane transport
D	0071934	biological_process	thiamine transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	18
Details	BINDING SITE FOR RESIDUE TPS A 400

Chain	Residue
A	TYR27
A	SER218
A	TYR221
A	GLU245
A	ASN279
A	TRP280
A	HOH402
A	HOH415
A	HOH438
A	HOH440
A	ASP59
A	GLY60
A	THR160
A	SER161
A	THR162
A	PRO163
A	TRP197
A	TYR215

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site_id	AC2
Number of Residues	18
Details	BINDING SITE FOR RESIDUE TPS B 400

Chain	Residue
B	TYR27
B	ASP59
B	GLY60
B	THR160
B	SER161
B	THR162
B	PRO163
B	TRP197
B	TYR215
B	SER218
B	TYR221
B	GLU245
B	ASN279
B	TRP280
B	HOH405
B	HOH412
B	HOH433
B	HOH453

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site_id	AC3
Number of Residues	16
Details	BINDING SITE FOR RESIDUE TPS C 400

Chain	Residue
C	TYR27
C	ASP59
C	GLY60
C	THR160
C	SER161
C	THR162
C	PRO163
C	TRP197
C	TYR215
C	SER218
C	GLU245
C	ASN279
C	TRP280
C	HOH401
C	HOH427
C	HOH437

---

site_id	AC4
Number of Residues	17
Details	BINDING SITE FOR RESIDUE TPS D 400

Chain	Residue
D	TYR27
D	ASP59
D	GLY60
D	THR160
D	SER161
D	THR162
D	PRO163
D	TRP197
D	TYR215
D	SER218
D	TYR221
D	GLU245
D	ASN279
D	TRP280
D	HOH404
D	HOH434
D	HOH521

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Functional Information from PROSITE/UniProt

site_id	PS01037
Number of Residues	18
Details	SBP_BACTERIAL_1 Bacterial extracellular solute-binding proteins, family 1 signature. PFDyGyfAFVYDknkLkN

Chain	Residue	Details
A	PRO119-ASN136

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18177053","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2QRY","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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