Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004797 | molecular_function | thymidine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006259 | biological_process | DNA metabolic process |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0009157 | biological_process | deoxyribonucleoside monophosphate biosynthetic process |
| A | 0016301 | molecular_function | kinase activity |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0046104 | biological_process | thymidine metabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0071897 | biological_process | DNA biosynthetic process |
| B | 0004797 | molecular_function | thymidine kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006259 | biological_process | DNA metabolic process |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0009157 | biological_process | deoxyribonucleoside monophosphate biosynthetic process |
| B | 0016301 | molecular_function | kinase activity |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0046104 | biological_process | thymidine metabolic process |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0071897 | biological_process | DNA biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 400 |
| Chain | Residue |
| A | CYS140 |
| A | CYS143 |
| A | CYS173 |
| A | CYS176 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 402 |
| Chain | Residue |
| B | CYS140 |
| B | CYS143 |
| B | CYS173 |
| B | CYS176 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE THM A 501 |
| Chain | Residue |
| A | GLN86 |
| A | PHE87 |
| A | LEU111 |
| A | THR114 |
| A | HIS115 |
| A | THR151 |
| A | GLU160 |
| A | ILE161 |
| A | ASP162 |
| A | VAL163 |
| A | GLY164 |
| A | TYR169 |
| A | GLU84 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE THM B 502 |
| Chain | Residue |
| B | GLU84 |
| B | GLN86 |
| B | PHE87 |
| B | LEU111 |
| B | THR114 |
| B | HIS115 |
| B | PHE120 |
| B | ILE161 |
| B | ASP162 |
| B | VAL163 |
| B | GLY164 |
| B | TYR169 |
Functional Information from PROSITE/UniProt
| site_id | PS00603 |
| Number of Residues | 14 |
| Details | TK_CELLULAR_TYPE Thymidine kinase cellular-type signature. GgqEkYiAvCRdCY |
| Chain | Residue | Details |
| A | GLY164-TYR177 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton acceptor => ECO:0000255 |
| Chain | Residue | Details |
| A | GLU84 | |
| B | GLU84 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 18 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | GLY10 | |
| B | GLY10 | |
| B | HIS53 | |
| B | HIS115 | |
| B | CYS140 | |
| B | CYS143 | |
| B | ILE161 | |
| B | TYR169 | |
| B | CYS173 | |
| B | CYS176 | |
| A | HIS53 | |
| A | HIS115 | |
| A | CYS140 | |
| A | CYS143 | |
| A | ILE161 | |
| A | TYR169 | |
| A | CYS173 | |
| A | CYS176 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | ASP83 | |
| B | ASP83 | |
