2QQD

N47A mutant of Pyruvoyl-dependent Arginine Decarboxylase from Methanococcus jannashii

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006520	biological_process	amino acid metabolic process
A	0006527	biological_process	arginine catabolic process
A	0008792	molecular_function	arginine decarboxylase activity
A	0016831	molecular_function	carboxy-lyase activity
B	0006520	biological_process	amino acid metabolic process
B	0006527	biological_process	arginine catabolic process
B	0008792	molecular_function	arginine decarboxylase activity
B	0016831	molecular_function	carboxy-lyase activity
C	0006520	biological_process	amino acid metabolic process
C	0006527	biological_process	arginine catabolic process
C	0008792	molecular_function	arginine decarboxylase activity
C	0016831	molecular_function	carboxy-lyase activity
D	0006520	biological_process	amino acid metabolic process
D	0006527	biological_process	arginine catabolic process
D	0008792	molecular_function	arginine decarboxylase activity
D	0016831	molecular_function	carboxy-lyase activity
E	0006520	biological_process	amino acid metabolic process
E	0006527	biological_process	arginine catabolic process
E	0008792	molecular_function	arginine decarboxylase activity
E	0016831	molecular_function	carboxy-lyase activity
F	0006520	biological_process	amino acid metabolic process
F	0006527	biological_process	arginine catabolic process
F	0008792	molecular_function	arginine decarboxylase activity
F	0016831	molecular_function	carboxy-lyase activity
G	0006520	biological_process	amino acid metabolic process
G	0006527	biological_process	arginine catabolic process
G	0008792	molecular_function	arginine decarboxylase activity
G	0016831	molecular_function	carboxy-lyase activity
H	0006520	biological_process	amino acid metabolic process
H	0006527	biological_process	arginine catabolic process
H	0008792	molecular_function	arginine decarboxylase activity
H	0016831	molecular_function	carboxy-lyase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE AG2 B 671

Chain	Residue
A	SER52
C	LEU38
C	GLY44
A	HOH689
B	ILE54
B	ILE107
B	MET108
B	GLU109
C	LEU31
C	PHE34
C	ASP35

---

site_id	AC2
Number of Residues	10
Details	BINDING SITE FOR RESIDUE AG2 A 671

Chain	Residue
A	LEU31
A	PHE34
A	ASP35
A	LEU38
A	GLY44
D	SER52
E	ILE54
E	ILE107
E	GLU109
E	ARG134

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PYR B 53

Chain	Residue
A	ILE51
B	ILE54
B	LEU106
B	ILE107

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PYR E 53

Chain	Residue
D	ILE51
D	SER52
E	ILE54
E	LEU106
E	ILE107

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MPD C 700

Chain	Residue
A	HOH689
C	LEU31
C	PHE34
C	TYR79

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MPD D 700

Chain	Residue
A	LEU31
A	PHE34
B	TYR79
D	ARG50
D	SER52
D	HOH732

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	SITE: Cleavage (non-hydrolytic)

Chain	Residue	Details
C	SER52
F	SER52
G	SER52
H	SER52

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	MOD_RES: Pyruvic acid (Ser) => ECO:0000269|PubMed:11980912

Chain	Residue	Details
C	SER53
F	SER53
G	SER53
H	SER53

---

Catalytic Information from CSA

site_id	MCSA1
Number of Residues	4
Details	M-CSA 707

Chain	Residue	Details
C	ALA47
C	SER52
C	SER53
C	GLU109	proton shuttle (general acid/base)

---

site_id	MCSA2
Number of Residues	4
Details	M-CSA 707

Chain	Residue	Details
F	ALA47
F	SER52
F	SER53
F	GLU109	proton shuttle (general acid/base)

---

site_id	MCSA3
Number of Residues	4
Details	M-CSA 707

Chain	Residue	Details
G	ALA47
G	SER52
G	SER53
G	GLU109	proton shuttle (general acid/base)

---

site_id	MCSA4
Number of Residues	4
Details	M-CSA 707

Chain	Residue	Details
H	ALA47
H	SER52
H	SER53
H	GLU109	proton shuttle (general acid/base)

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