Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008234 | molecular_function | cysteine-type peptidase activity |
| B | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008234 | molecular_function | cysteine-type peptidase activity |
| C | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| C | 0006508 | biological_process | proteolysis |
| C | 0008234 | molecular_function | cysteine-type peptidase activity |
| D | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| D | 0006508 | biological_process | proteolysis |
| D | 0008234 | molecular_function | cysteine-type peptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE CIT D 850 |
| Chain | Residue |
| A | ARG187 |
| D | VAL592 |
| B | PRO227 |
| B | CYS290 |
| B | VAL292 |
| C | ARG487 |
| D | HOH36 |
| D | HOH135 |
| D | TYR523 |
| D | PRO527 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR CHAIN E OF INHIBITOR AC-IEPD_CHO |
| Chain | Residue |
| A | VAL86 |
| A | ARG87 |
| A | HIS144 |
| A | GLY145 |
| A | GLN184 |
| A | CYS186 |
| B | SER231 |
| B | TRP232 |
| B | ARG233 |
| B | PRO235 |
| B | TRP240 |
| B | GLN276 |
| B | HOH335 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR CHAIN F OF INHIBITOR AC-IEPD_CHO |
| Chain | Residue |
| C | ARG387 |
| C | HIS444 |
| C | GLY445 |
| C | GLN484 |
| C | CYS486 |
| D | TYR530 |
| D | SER531 |
| D | TRP532 |
| D | ARG533 |
| D | PRO535 |
| D | TRP540 |
| D | SER575 |
| D | GLN576 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR CHAIN G OF QGHGE |
| Chain | Residue |
| A | GLN59 |
| B | GLN260 |
| B | TYR300 |
| B | SER302 |
| C | GLN359 |
| D | GLN560 |
| D | TYR600 |
| D | SER602 |
| G | HOH217 |
Functional Information from PROSITE/UniProt
| site_id | PS01121 |
| Number of Residues | 15 |
| Details | CASPASE_HIS Caspase family histidine active site. HtnaaCfaCiLLSHG |
| Chain | Residue | Details |
| A | HIS131-GLY145 | |
| site_id | PS01122 |
| Number of Residues | 12 |
| Details | CASPASE_CYS Caspase family cysteine active site. KPKLFFIQACRG |
| Chain | Residue | Details |
| A | LYS177-GLY188 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| B | TYR223 | |
| D | TYR523 | |
| Chain | Residue | Details |
| B | ARG233 | |
| D | ARG533 | |
| Chain | Residue | Details |
| A | SER47 | |
| C | PHE336 | |
| C | MET345 | |
| C | SER347 | |
| B | SER239 | |
| D | SER539 | |
| Chain | Residue | Details |
| A | ARG187 | |
| C | ARG487 | |
| Chain | Residue | Details |
| A | SER30 | |
| C | SER330 | |
| Chain | Residue | Details |
| A | SER37 | |
| C | SER337 | |
| Chain | Residue | Details |
| A | THR173 | |
| C | THR473 | |
