2QJH
M. jannaschii ADH synthase covalently bound to dihydroxyacetone phosphate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
| A | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| A | 0016744 | molecular_function | transketolase or transaldolase activity |
| A | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016836 | molecular_function | hydro-lyase activity |
| B | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
| B | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| B | 0016744 | molecular_function | transketolase or transaldolase activity |
| B | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| B | 0016829 | molecular_function | lyase activity |
| B | 0016836 | molecular_function | hydro-lyase activity |
| C | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
| C | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| C | 0016744 | molecular_function | transketolase or transaldolase activity |
| C | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| C | 0016829 | molecular_function | lyase activity |
| C | 0016836 | molecular_function | hydro-lyase activity |
| D | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
| D | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| D | 0016744 | molecular_function | transketolase or transaldolase activity |
| D | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| D | 0016829 | molecular_function | lyase activity |
| D | 0016836 | molecular_function | hydro-lyase activity |
| E | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
| E | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| E | 0016744 | molecular_function | transketolase or transaldolase activity |
| E | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| E | 0016829 | molecular_function | lyase activity |
| E | 0016836 | molecular_function | hydro-lyase activity |
| F | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
| F | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| F | 0016744 | molecular_function | transketolase or transaldolase activity |
| F | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| F | 0016829 | molecular_function | lyase activity |
| F | 0016836 | molecular_function | hydro-lyase activity |
| G | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
| G | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| G | 0016744 | molecular_function | transketolase or transaldolase activity |
| G | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| G | 0016829 | molecular_function | lyase activity |
| G | 0016836 | molecular_function | hydro-lyase activity |
| H | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
| H | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| H | 0016744 | molecular_function | transketolase or transaldolase activity |
| H | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| H | 0016829 | molecular_function | lyase activity |
| H | 0016836 | molecular_function | hydro-lyase activity |
| I | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
| I | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| I | 0016744 | molecular_function | transketolase or transaldolase activity |
| I | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| I | 0016829 | molecular_function | lyase activity |
| I | 0016836 | molecular_function | hydro-lyase activity |
| J | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
| J | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| J | 0016744 | molecular_function | transketolase or transaldolase activity |
| J | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| J | 0016829 | molecular_function | lyase activity |
| J | 0016836 | molecular_function | hydro-lyase activity |
| K | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
| K | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| K | 0016744 | molecular_function | transketolase or transaldolase activity |
| K | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| K | 0016829 | molecular_function | lyase activity |
| K | 0016836 | molecular_function | hydro-lyase activity |
| L | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
| L | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| L | 0016744 | molecular_function | transketolase or transaldolase activity |
| L | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| L | 0016829 | molecular_function | lyase activity |
| L | 0016836 | molecular_function | hydro-lyase activity |
| M | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
| M | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| M | 0016744 | molecular_function | transketolase or transaldolase activity |
| M | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| M | 0016829 | molecular_function | lyase activity |
| M | 0016836 | molecular_function | hydro-lyase activity |
| N | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
| N | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| N | 0016744 | molecular_function | transketolase or transaldolase activity |
| N | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| N | 0016829 | molecular_function | lyase activity |
| N | 0016836 | molecular_function | hydro-lyase activity |
| O | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
| O | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| O | 0016744 | molecular_function | transketolase or transaldolase activity |
| O | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| O | 0016829 | molecular_function | lyase activity |
| O | 0016836 | molecular_function | hydro-lyase activity |
| P | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
| P | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| P | 0016744 | molecular_function | transketolase or transaldolase activity |
| P | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| P | 0016829 | molecular_function | lyase activity |
| P | 0016836 | molecular_function | hydro-lyase activity |
| Q | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
| Q | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| Q | 0016744 | molecular_function | transketolase or transaldolase activity |
| Q | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| Q | 0016829 | molecular_function | lyase activity |
| Q | 0016836 | molecular_function | hydro-lyase activity |
| R | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
| R | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| R | 0016744 | molecular_function | transketolase or transaldolase activity |
| R | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| R | 0016829 | molecular_function | lyase activity |
| R | 0016836 | molecular_function | hydro-lyase activity |
| S | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
| S | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| S | 0016744 | molecular_function | transketolase or transaldolase activity |
| S | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| S | 0016829 | molecular_function | lyase activity |
| S | 0016836 | molecular_function | hydro-lyase activity |
| T | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
| T | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| T | 0016744 | molecular_function | transketolase or transaldolase activity |
| T | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| T | 0016829 | molecular_function | lyase activity |
| T | 0016836 | molecular_function | hydro-lyase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 13P A 501 |
| Chain | Residue |
| A | PRO31 |
| A | ARG238 |
| A | ASP33 |
| A | HIS34 |
| A | LYS184 |
| A | ALA208 |
| A | GLY209 |
| A | GLY210 |
| A | VAL236 |
| A | GLY237 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 13P B 501 |
| Chain | Residue |
| B | PRO31 |
| B | ASP33 |
| B | HIS34 |
| B | LYS184 |
| B | ALA208 |
| B | GLY209 |
| B | GLY210 |
| B | VAL236 |
| B | GLY237 |
| B | ARG238 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE 13P C 501 |
| Chain | Residue |
| C | PRO31 |
| C | ASP33 |
| C | HIS34 |
| C | LYS184 |
| C | ALA208 |
| C | GLY209 |
| C | GLY210 |
| C | VAL236 |
| C | GLY237 |
| C | ARG238 |
| C | HOH508 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 13P D 501 |
| Chain | Residue |
| D | PRO31 |
| D | ASP33 |
| D | HIS34 |
| D | LYS184 |
| D | ALA208 |
| D | GLY209 |
| D | GLY210 |
| D | VAL236 |
| D | GLY237 |
| D | ARG238 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 13P E 501 |
| Chain | Residue |
| E | PRO31 |
| E | ASP33 |
| E | HIS34 |
| E | LYS184 |
| E | ALA208 |
| E | GLY209 |
| E | GLY210 |
| E | VAL236 |
| E | GLY237 |
| E | ARG238 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 13P F 501 |
| Chain | Residue |
| F | PRO31 |
| F | ASP33 |
| F | HIS34 |
| F | LYS184 |
| F | ALA208 |
| F | GLY209 |
| F | GLY210 |
| F | VAL236 |
| F | GLY237 |
| F | ARG238 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 13P G 501 |
| Chain | Residue |
| G | PRO31 |
| G | ASP33 |
| G | HIS34 |
| G | LYS184 |
| G | ALA208 |
| G | GLY209 |
| G | GLY210 |
| G | VAL236 |
| G | GLY237 |
| G | ARG238 |
| site_id | AC8 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE 13P H 501 |
| Chain | Residue |
| H | PRO31 |
| H | ASP33 |
| H | HIS34 |
| H | LYS184 |
| H | ALA208 |
| H | GLY209 |
| H | GLY210 |
| H | VAL236 |
| H | GLY237 |
| H | ARG238 |
| H | HOH509 |
| site_id | AC9 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE 13P I 501 |
| Chain | Residue |
| I | PRO31 |
| I | ASP33 |
| I | HIS34 |
| I | LYS184 |
| I | ALA208 |
| I | GLY209 |
| I | GLY210 |
| I | VAL236 |
| I | GLY237 |
| I | ARG238 |
| I | HOH523 |
| site_id | BC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE 13P J 501 |
| Chain | Residue |
| J | GLY210 |
| J | VAL236 |
| J | GLY237 |
| J | ARG238 |
| J | HOH510 |
| J | PRO31 |
| J | ASP33 |
| J | HIS34 |
| J | LYS184 |
| J | ALA208 |
| J | GLY209 |
| site_id | BC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE 13P K 501 |
| Chain | Residue |
| K | PRO31 |
| K | ASP33 |
| K | HIS34 |
| K | LYS184 |
| K | ALA208 |
| K | GLY209 |
| K | GLY210 |
| K | VAL236 |
| K | GLY237 |
| K | ARG238 |
| K | HOH513 |
| site_id | BC3 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE 13P L 501 |
| Chain | Residue |
| L | PRO31 |
| L | ASP33 |
| L | HIS34 |
| L | LYS184 |
| L | ALA208 |
| L | GLY209 |
| L | GLY210 |
| L | VAL236 |
| L | GLY237 |
| L | ARG238 |
| L | HOH520 |
| site_id | BC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 13P M 501 |
| Chain | Residue |
| M | PRO31 |
| M | ASP33 |
| M | HIS34 |
| M | LYS184 |
| M | ALA208 |
| M | GLY209 |
| M | GLY210 |
| M | VAL236 |
| M | GLY237 |
| M | ARG238 |
| site_id | BC5 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 13P N 501 |
| Chain | Residue |
| N | PRO31 |
| N | ASP33 |
| N | HIS34 |
| N | LYS184 |
| N | ALA208 |
| N | GLY209 |
| N | GLY210 |
| N | VAL236 |
| N | GLY237 |
| N | ARG238 |
| site_id | BC6 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 13P O 501 |
| Chain | Residue |
| O | PRO31 |
| O | ASP33 |
| O | HIS34 |
| O | LYS184 |
| O | ALA208 |
| O | GLY209 |
| O | GLY210 |
| O | VAL236 |
| O | GLY237 |
| O | ARG238 |
| site_id | BC7 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 13P P 501 |
| Chain | Residue |
| P | PRO31 |
| P | ASP33 |
| P | HIS34 |
| P | LYS184 |
| P | ALA208 |
| P | GLY209 |
| P | GLY210 |
| P | VAL236 |
| P | GLY237 |
| P | ARG238 |
| site_id | BC8 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 13P Q 501 |
| Chain | Residue |
| Q | PRO31 |
| Q | ASP33 |
| Q | HIS34 |
| Q | LYS184 |
| Q | ALA208 |
| Q | GLY209 |
| Q | GLY210 |
| Q | VAL236 |
| Q | GLY237 |
| Q | ARG238 |
| site_id | BC9 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 13P R 501 |
| Chain | Residue |
| R | PRO31 |
| R | ASP33 |
| R | HIS34 |
| R | LYS184 |
| R | ALA208 |
| R | GLY209 |
| R | GLY210 |
| R | VAL236 |
| R | GLY237 |
| R | ARG238 |
| site_id | CC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 13P S 501 |
| Chain | Residue |
| S | PRO31 |
| S | ASP33 |
| S | HIS34 |
| S | LYS184 |
| S | ALA208 |
| S | GLY209 |
| S | GLY210 |
| S | VAL236 |
| S | GLY237 |
| S | ARG238 |
| site_id | CC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 13P T 501 |
| Chain | Residue |
| T | PRO31 |
| T | ASP33 |
| T | HIS34 |
| T | LYS184 |
| T | ALA208 |
| T | GLY209 |
| T | GLY210 |
| T | VAL236 |
| T | GLY237 |
| T | ARG238 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 20 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"17713928","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"17713928","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 20 |
| Details | Active site: {"description":"Schiff-base intermediate with substrate","evidences":[{"source":"PubMed","id":"17713928","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 160 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17713928","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ok4 |
| Chain | Residue | Details |
| A | ASP33 | |
| A | LYS184 | |
| A | TYR153 |
| site_id | CSA10 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ok4 |
| Chain | Residue | Details |
| J | ASP33 | |
| J | LYS184 | |
| J | TYR153 |
| site_id | CSA11 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ok4 |
| Chain | Residue | Details |
| K | ASP33 | |
| K | LYS184 | |
| K | TYR153 |
| site_id | CSA12 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ok4 |
| Chain | Residue | Details |
| L | ASP33 | |
| L | LYS184 | |
| L | TYR153 |
| site_id | CSA13 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ok4 |
| Chain | Residue | Details |
| M | ASP33 | |
| M | LYS184 | |
| M | TYR153 |
| site_id | CSA14 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ok4 |
| Chain | Residue | Details |
| N | ASP33 | |
| N | LYS184 | |
| N | TYR153 |
| site_id | CSA15 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ok4 |
| Chain | Residue | Details |
| O | ASP33 | |
| O | LYS184 | |
| O | TYR153 |
| site_id | CSA16 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ok4 |
| Chain | Residue | Details |
| P | ASP33 | |
| P | LYS184 | |
| P | TYR153 |
| site_id | CSA17 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ok4 |
| Chain | Residue | Details |
| Q | ASP33 | |
| Q | LYS184 | |
| Q | TYR153 |
| site_id | CSA18 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ok4 |
| Chain | Residue | Details |
| R | ASP33 | |
| R | LYS184 | |
| R | TYR153 |
| site_id | CSA19 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ok4 |
| Chain | Residue | Details |
| S | ASP33 | |
| S | LYS184 | |
| S | TYR153 |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ok4 |
| Chain | Residue | Details |
| B | ASP33 | |
| B | LYS184 | |
| B | TYR153 |
| site_id | CSA20 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ok4 |
| Chain | Residue | Details |
| T | ASP33 | |
| T | LYS184 | |
| T | TYR153 |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ok4 |
| Chain | Residue | Details |
| C | ASP33 | |
| C | LYS184 | |
| C | TYR153 |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ok4 |
| Chain | Residue | Details |
| D | ASP33 | |
| D | LYS184 | |
| D | TYR153 |
| site_id | CSA5 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ok4 |
| Chain | Residue | Details |
| E | ASP33 | |
| E | LYS184 | |
| E | TYR153 |
| site_id | CSA6 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ok4 |
| Chain | Residue | Details |
| F | ASP33 | |
| F | LYS184 | |
| F | TYR153 |
| site_id | CSA7 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ok4 |
| Chain | Residue | Details |
| G | ASP33 | |
| G | LYS184 | |
| G | TYR153 |
| site_id | CSA8 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ok4 |
| Chain | Residue | Details |
| H | ASP33 | |
| H | LYS184 | |
| H | TYR153 |
| site_id | CSA9 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ok4 |
| Chain | Residue | Details |
| I | ASP33 | |
| I | LYS184 | |
| I | TYR153 |
