2QIO
X-Ray Structure of Enoyl-Acyl Carrier Protein Reductase from Bacillus Anthracis with Triclosan
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000166 | molecular_function | nucleotide binding |
A | 0004318 | molecular_function | enoyl-[acyl-carrier-protein] reductase (NADH) activity |
A | 0006633 | biological_process | fatty acid biosynthetic process |
A | 0016491 | molecular_function | oxidoreductase activity |
B | 0000166 | molecular_function | nucleotide binding |
B | 0004318 | molecular_function | enoyl-[acyl-carrier-protein] reductase (NADH) activity |
B | 0006633 | biological_process | fatty acid biosynthetic process |
B | 0016491 | molecular_function | oxidoreductase activity |
C | 0000166 | molecular_function | nucleotide binding |
C | 0004318 | molecular_function | enoyl-[acyl-carrier-protein] reductase (NADH) activity |
C | 0006633 | biological_process | fatty acid biosynthetic process |
C | 0016491 | molecular_function | oxidoreductase activity |
D | 0000166 | molecular_function | nucleotide binding |
D | 0004318 | molecular_function | enoyl-[acyl-carrier-protein] reductase (NADH) activity |
D | 0006633 | biological_process | fatty acid biosynthetic process |
D | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 27 |
Details | BINDING SITE FOR RESIDUE NAD A 501 |
Chain | Residue |
A | GLY13 |
A | ILE94 |
A | ALA95 |
A | ILE120 |
A | LEU145 |
A | THR146 |
A | TYR147 |
A | LYS164 |
A | ALA190 |
A | PRO192 |
A | ILE193 |
A | ALA15 |
A | THR195 |
A | LEU196 |
A | SER197 |
A | HOH607 |
A | HOH608 |
A | HOH613 |
A | HOH622 |
A | HOH627 |
A | SER19 |
A | ILE20 |
A | ALA40 |
A | LEU44 |
A | CYS65 |
A | ASP66 |
A | CYS93 |
site_id | AC2 |
Number of Residues | 26 |
Details | BINDING SITE FOR RESIDUE NAD B 502 |
Chain | Residue |
B | GLY13 |
B | ALA15 |
B | SER19 |
B | ILE20 |
B | ALA40 |
B | LEU44 |
B | CYS65 |
B | ASP66 |
B | CYS93 |
B | ILE94 |
B | ALA95 |
B | LEU145 |
B | THR146 |
B | TYR147 |
B | LYS164 |
B | ALA190 |
B | GLY191 |
B | PRO192 |
B | ILE193 |
B | THR195 |
B | LEU196 |
B | SER197 |
B | HOH605 |
B | HOH611 |
B | HOH614 |
B | HOH634 |
site_id | AC3 |
Number of Residues | 26 |
Details | BINDING SITE FOR RESIDUE NAD C 503 |
Chain | Residue |
C | GLY13 |
C | ALA15 |
C | SER19 |
C | ILE20 |
C | ALA40 |
C | LEU44 |
C | CYS65 |
C | ASP66 |
C | CYS93 |
C | ILE94 |
C | ALA95 |
C | LEU145 |
C | THR146 |
C | TYR147 |
C | LYS164 |
C | ALA190 |
C | GLY191 |
C | PRO192 |
C | ILE193 |
C | THR195 |
C | SER197 |
C | HOH611 |
C | HOH613 |
C | HOH616 |
C | HOH624 |
C | HOH629 |
site_id | AC4 |
Number of Residues | 27 |
Details | BINDING SITE FOR RESIDUE NAD D 504 |
Chain | Residue |
D | HOH614 |
D | HOH618 |
D | HOH638 |
D | HOH640 |
D | HOH655 |
D | HOH664 |
D | HOH677 |
D | GLY13 |
D | ALA15 |
D | SER19 |
D | ILE20 |
D | LEU44 |
D | CYS65 |
D | ASP66 |
D | CYS93 |
D | ILE94 |
D | ALA95 |
D | LEU145 |
D | THR146 |
D | TYR147 |
D | LYS164 |
D | ALA190 |
D | GLY191 |
D | PRO192 |
D | ILE193 |
D | THR195 |
D | SER197 |
site_id | AC5 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE TCL A 601 |
Chain | Residue |
A | ALA95 |
A | ALA97 |
A | LEU102 |
A | TYR147 |
A | TYR157 |
A | SER197 |
site_id | AC6 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE TCL B 602 |
Chain | Residue |
B | ALA95 |
B | ALA97 |
B | LEU102 |
B | TYR147 |
B | TYR157 |
B | MET160 |
B | SER197 |
site_id | AC7 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE TCL C 603 |
Chain | Residue |
C | ALA95 |
C | ALA97 |
C | TYR147 |
C | TYR157 |
C | SER197 |
C | ALA198 |
site_id | AC8 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE TCL D 604 |
Chain | Residue |
D | ALA95 |
D | ALA97 |
D | TYR147 |
D | TYR157 |
D | SER197 |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1qsg |
Chain | Residue | Details |
A | LYS164 | |
A | TYR157 |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1qsg |
Chain | Residue | Details |
B | LYS164 | |
B | TYR157 |
site_id | CSA3 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1qsg |
Chain | Residue | Details |
C | LYS164 | |
C | TYR157 |
site_id | CSA4 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1qsg |
Chain | Residue | Details |
D | LYS164 | |
D | TYR157 |
site_id | CSA5 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1qsg |
Chain | Residue | Details |
A | LYS164 | |
A | MET160 |
site_id | CSA6 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1qsg |
Chain | Residue | Details |
B | LYS164 | |
B | MET160 |
site_id | CSA7 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1qsg |
Chain | Residue | Details |
C | LYS164 | |
C | MET160 |
site_id | CSA8 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1qsg |
Chain | Residue | Details |
D | LYS164 | |
D | MET160 |