2QH6
Crystal Structure of the Estrogen Receptor Alpha Ligand Binding Domain Complexed with an Oxabicyclic diarylethylene Compound
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE ODE A 700 |
| Chain | Residue |
| A | MET343 |
| A | GLY521 |
| A | HIS524 |
| A | LEU525 |
| A | LEU540 |
| A | LEU346 |
| A | THR347 |
| A | GLU353 |
| A | LEU384 |
| A | ARG394 |
| A | PHE404 |
| A | MET421 |
| A | PHE425 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE ODE B 800 |
| Chain | Residue |
| B | LEU346 |
| B | THR347 |
| B | GLU353 |
| B | LEU384 |
| B | MET388 |
| B | ARG394 |
| B | MET421 |
| B | ILE424 |
| B | PHE425 |
| B | LEU428 |
| B | HIS524 |
| B | LEU525 |
| B | LEU536 |
| B | LEU540 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphotyrosine; by Tyr-kinases => ECO:0000269|PubMed:7539106 |
| Chain | Residue | Details |
| A | SER537 | |
| B | SER537 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | LIPID: S-palmitoyl cysteine => ECO:0000250 |
| Chain | Residue | Details |
| A | CYS447 | |
| B | CYS447 |
