2QAP
Fructose-1,6-bisphosphate aldolase from Leishmania mexicana
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006096 | biological_process | glycolytic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0030388 | biological_process | fructose 1,6-bisphosphate metabolic process |
| B | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006096 | biological_process | glycolytic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0030388 | biological_process | fructose 1,6-bisphosphate metabolic process |
| C | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0006096 | biological_process | glycolytic process |
| C | 0016829 | molecular_function | lyase activity |
| C | 0030388 | biological_process | fructose 1,6-bisphosphate metabolic process |
| D | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0006096 | biological_process | glycolytic process |
| D | 0016829 | molecular_function | lyase activity |
| D | 0030388 | biological_process | fructose 1,6-bisphosphate metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 A 3001 |
| Chain | Residue |
| A | SER281 |
| A | GLY282 |
| A | ALA312 |
| A | ARG313 |
| A | PO43002 |
| A | HOH3014 |
| A | HOH3471 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 A 3002 |
| Chain | Residue |
| A | LEU280 |
| A | PO43001 |
| A | HOH3004 |
| A | HOH3015 |
| A | GLU197 |
| A | GLU199 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PO4 A 3003 |
| Chain | Residue |
| A | GLU216 |
| A | HIS217 |
| A | ARG220 |
| A | HOH3311 |
| A | HOH3312 |
| A | HOH3394 |
| D | ASN15 |
| D | HOH3489 |
| D | HOH3490 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 B 3004 |
| Chain | Residue |
| B | GLY282 |
| B | ALA312 |
| B | ARG313 |
| B | HOH3190 |
| B | HOH3213 |
| B | HOH3429 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PO4 B 3005 |
| Chain | Residue |
| B | GLU216 |
| B | HIS217 |
| B | ARG220 |
| B | HOH3235 |
| B | HOH3282 |
| B | HOH3337 |
| C | ASN15 |
| C | HOH3015 |
| C | HOH3237 |
| site_id | AC6 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PO4 C 3006 |
| Chain | Residue |
| C | ARG52 |
| C | SER281 |
| C | GLY282 |
| C | ALA312 |
| C | ARG313 |
| C | PO43007 |
| C | HOH3012 |
| C | HOH3085 |
| C | HOH3483 |
| C | HOH3506 |
| C | HOH3563 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 C 3007 |
| Chain | Residue |
| C | GLU197 |
| C | GLU199 |
| C | PO43006 |
| C | HOH3085 |
| C | HOH3506 |
| C | HOH3559 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PO4 C 3008 |
| Chain | Residue |
| B | ASN15 |
| B | HOH3010 |
| B | HOH3259 |
| B | HOH3354 |
| C | GLU216 |
| C | HIS217 |
| C | ARG220 |
| C | HOH3280 |
| C | HOH3313 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 D 3009 |
| Chain | Residue |
| D | ARG52 |
| D | SER281 |
| D | GLY282 |
| D | ALA312 |
| D | ARG313 |
| D | PO43010 |
| D | HOH3176 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 D 3010 |
| Chain | Residue |
| D | GLU197 |
| D | GLU199 |
| D | LEU280 |
| D | PO43009 |
| D | HOH3159 |
| D | HOH3383 |
| site_id | BC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 D 3011 |
| Chain | Residue |
| A | ASN15 |
| A | HOH3211 |
| A | HOH3291 |
| D | GLU216 |
| D | HIS217 |
| D | ARG220 |
| D | HOH3376 |
| D | HOH3406 |
Functional Information from PROSITE/UniProt
| site_id | PS00158 |
| Number of Residues | 11 |
| Details | ALDOLASE_CLASS_I Fructose-bisphosphate aldolase class-I active site. ViWEGcLLKPN |
| Chain | Residue | Details |
| A | VAL231-ASN241 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ald |
| Chain | Residue | Details |
| A | ASP43 | |
| A | GLU197 | |
| A | LYS239 |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ald |
| Chain | Residue | Details |
| B | ASP43 | |
| B | GLU197 | |
| B | LYS239 |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ald |
| Chain | Residue | Details |
| C | ASP43 | |
| C | GLU197 | |
| C | LYS239 |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ald |
| Chain | Residue | Details |
| D | ASP43 | |
| D | GLU197 | |
| D | LYS239 |
