2QA1

Crystal structure of PgaE, an aromatic hydroxylase involved in angucycline biosynthesis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0016491	molecular_function	oxidoreductase activity
A	0016709	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
A	0046872	molecular_function	metal ion binding
A	0071949	molecular_function	FAD binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 601

Chain	Residue
A	HIS-1
A	GLU36
A	HIS118
A	GLU138

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site_id	AC2
Number of Residues	39
Details	BINDING SITE FOR RESIDUE FAD A 500

Chain	Residue
A	LEU31
A	GLU32
A	ARG33
A	LEU34
A	ARG42
A	GLY43
A	GLN96
A	HIS118
A	GLU119
A	VAL120
A	CYS151
A	ASP152
A	GLY153
A	SER157
A	LEU177
A	GLY274
A	ASP275
A	GLY285
A	GLN286
A	GLY287
A	MET288
A	ASN289
A	SER291
A	GOL608
A	HOH648
A	HOH681
A	HOH698
A	HOH779
A	HOH780
A	HOH781
A	HOH791
A	HOH886
A	HOH891
A	HOH958
A	VAL8
A	GLY9
A	GLY11
A	PRO12
A	ALA13

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 602

Chain	Residue
A	HIS73
A	GLY284
A	GLY285
A	HOH716

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 603

Chain	Residue
A	THR398
A	THR400
A	ARG401
A	HOH634
A	HOH966

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 604

Chain	Residue
A	TYR377
A	ASP378
A	VAL379
A	GLY380
A	LEU387
A	HOH767

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 605

Chain	Residue
A	HIS410
A	HOH755
A	HOH758
A	HOH793

---

site_id	AC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE GOL A 606

Chain	Residue
A	ARG267

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site_id	AC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A 607

Chain	Residue
A	LEU23
A	ALA24
A	THR411
A	ALA412
A	ARG413
A	HOH656
A	HOH911

---

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 608

Chain	Residue
A	ASP275
A	ILE279
A	HIS280
A	PRO282
A	FAD500

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