2Q9E
Structure of spin-labeled T4 lysozyme mutant S44R1
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003796 | molecular_function | lysozyme activity |
| A | 0009253 | biological_process | peptidoglycan catabolic process |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| A | 0030430 | cellular_component | host cell cytoplasm |
| A | 0031640 | biological_process | killing of cells of another organism |
| A | 0042742 | biological_process | defense response to bacterium |
| A | 0044659 | biological_process | viral release from host cell by cytolysis |
| B | 0003796 | molecular_function | lysozyme activity |
| B | 0009253 | biological_process | peptidoglycan catabolic process |
| B | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| B | 0030430 | cellular_component | host cell cytoplasm |
| B | 0031640 | biological_process | killing of cells of another organism |
| B | 0042742 | biological_process | defense response to bacterium |
| B | 0044659 | biological_process | viral release from host cell by cytolysis |
| C | 0003796 | molecular_function | lysozyme activity |
| C | 0009253 | biological_process | peptidoglycan catabolic process |
| C | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| C | 0030430 | cellular_component | host cell cytoplasm |
| C | 0031640 | biological_process | killing of cells of another organism |
| C | 0042742 | biological_process | defense response to bacterium |
| C | 0044659 | biological_process | viral release from host cell by cytolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MTN A 844 |
| Chain | Residue |
| A | CYS44 |
| A | HED900 |
| A | HOH911 |
| A | HOH1046 |
| B | ALA134 |
| B | TYR139 |
| B | ARG154 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MTN B 844 |
| Chain | Residue |
| A | TYR139 |
| A | ARG154 |
| B | CYS44 |
| A | ALA130 |
| A | ALA134 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE MTN C 844 |
| Chain | Residue |
| C | CYS44 |
| C | GLU45 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE HED A 900 |
| Chain | Residue |
| A | ASN40 |
| A | LYS43 |
| A | ASP47 |
| A | ASN53 |
| A | ALA55 |
| A | MTN844 |
| A | HOH1045 |
| B | VAL131 |
| B | LYS135 |
| B | TYR139 |
| B | HOH921 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE HED B 910 |
| Chain | Residue |
| A | VAL131 |
| A | LYS135 |
| A | TYR139 |
| B | ASN40 |
| B | LYS43 |
| B | ASP47 |
| B | THR54 |
| B | ALA55 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE HED B 920 |
| Chain | Residue |
| A | HOH1000 |
| B | VAL71 |
| B | HOH926 |
| B | HOH952 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Proton donor/acceptor => ECO:0000255|HAMAP-Rule:MF_04110, ECO:0000269|PubMed:3382407, ECO:0000269|PubMed:7831309, ECO:0000269|PubMed:8266098 |
| Chain | Residue | Details |
| A | GLU11 | |
| B | GLU11 | |
| C | GLU11 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | ACT_SITE: Proton donor/acceptor => ECO:0000255|HAMAP-Rule:MF_04110, ECO:0000269|PubMed:1892846, ECO:0000269|PubMed:3382407, ECO:0000269|PubMed:7831309, ECO:0000269|PubMed:8266098 |
| Chain | Residue | Details |
| A | ASP20 | |
| B | ASP20 | |
| C | ASP20 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:8266098 |
| Chain | Residue | Details |
| A | LEU32 | |
| A | PHE104 | |
| B | LEU32 | |
| B | PHE104 | |
| C | LEU32 | |
| C | PHE104 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000303|PubMed:7831309 |
| Chain | Residue | Details |
| A | SER117 | |
| A | ASN132 | |
| B | SER117 | |
| B | ASN132 | |
| C | SER117 | |
| C | ASN132 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 206l |
| Chain | Residue | Details |
| A | GLU11 | |
| A | ASP20 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 206l |
| Chain | Residue | Details |
| B | GLU11 | |
| B | ASP20 |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 206l |
| Chain | Residue | Details |
| C | GLU11 | |
| C | ASP20 |
| site_id | MCSA1 |
| Number of Residues | 2 |
| Details | M-CSA 921 |
| Chain | Residue | Details |
| A | GLU11 | proton shuttle (general acid/base) |
| A | ASP20 | covalent catalysis |
| site_id | MCSA2 |
| Number of Residues | 2 |
| Details | M-CSA 921 |
| Chain | Residue | Details |
| B | GLU11 | proton shuttle (general acid/base) |
| B | ASP20 | covalent catalysis |
| site_id | MCSA3 |
| Number of Residues | 2 |
| Details | M-CSA 921 |
| Chain | Residue | Details |
| C | GLU11 | proton shuttle (general acid/base) |
| C | ASP20 | covalent catalysis |
