Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004791 | molecular_function | thioredoxin-disulfide reductase (NADPH) activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019430 | biological_process | removal of superoxide radicals |
| A | 0045454 | biological_process | cell redox homeostasis |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004791 | molecular_function | thioredoxin-disulfide reductase (NADPH) activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0019430 | biological_process | removal of superoxide radicals |
| B | 0045454 | biological_process | cell redox homeostasis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE FAD A 348 |
| Chain | Residue |
| A | GLY15 |
| A | ILE46 |
| A | ASN54 |
| A | ASP85 |
| A | GLU86 |
| A | ALA118 |
| A | THR119 |
| A | GLY120 |
| A | CYS145 |
| A | GLY283 |
| A | ASP284 |
| A | GLY17 |
| A | ARG291 |
| A | GLN292 |
| A | LEU293 |
| A | SER296 |
| A | PRO18 |
| A | ALA19 |
| A | LEU37 |
| A | GLU38 |
| A | LYS39 |
| A | GLY44 |
| A | GLN45 |
| site_id | AC2 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE FAD B 448 |
| Chain | Residue |
| A | TYR26 |
| B | GLY15 |
| B | GLY17 |
| B | PRO18 |
| B | ALA19 |
| B | LEU37 |
| B | GLU38 |
| B | LYS39 |
| B | GLY44 |
| B | GLN45 |
| B | ILE46 |
| B | SER49 |
| B | ASN54 |
| B | ASP85 |
| B | GLU86 |
| B | ALA118 |
| B | THR119 |
| B | GLY120 |
| B | CYS145 |
| B | GLY283 |
| B | ASP284 |
| B | ARG291 |
| B | GLN292 |
| B | LEU293 |
| B | SER296 |
Functional Information from PROSITE/UniProt
| site_id | PS00573 |
| Number of Residues | 21 |
| Details | PYRIDINE_REDOX_2 Pyridine nucleotide-disulphide oxidoreductases class-II active site. CatCDGff..YkgkkVvVIGGGD |
| Chain | Residue | Details |
| A | CYS142-ASP162 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1tde |
| Chain | Residue | Details |
| A | CYS142 | |
| A | CYS145 | |
| A | ASP146 | |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1tde |
| Chain | Residue | Details |
| B | CYS142 | |
| B | CYS145 | |
| B | ASP146 | |
