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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

2Q7I

The Wild Type Androgen Receptor Ligand Binding Domain Bound with Testosterone and an AR 20-30 Peptide

Functional Information from PDB Data
site_idAC1
Number of Residues7
DetailsBINDING SITE FOR RESIDUE SO4 A 202
ChainResidue
AHOH72
AHOH158
ASER696
APHE697
ALYS777
AARG779
ASER853
site_idAC2
Number of Residues6
DetailsBINDING SITE FOR RESIDUE SO4 A 203
ChainResidue
AHIS714
ALYS717
ASER908
ALYS910
AHOH182
AHOH184
site_idAC3
Number of Residues8
DetailsBINDING SITE FOR RESIDUE TES A 205
ChainResidue
ALEU704
AASN705
AGLN711
AMET745
AMET749
AARG752
APHE764
ATHR877
site_idAC4
Number of Residues6
DetailsBINDING SITE FOR RESIDUE GOL A 201
ChainResidue
AHOH146
APRO682
AVAL685
AGLN711
AVAL715
AMET745
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"15563469","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16641486","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17591767","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25091737","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1T5Z","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1T63","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1T65","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1XJ7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2AM9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2AMA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2AMB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PIO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PIP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PIR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PIT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PIU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PIV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PIW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PIX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PKL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PNU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2Q7I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2Q7J","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2Q7K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2Q7L","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2YHD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2YLO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2YLP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2YLQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3L3X","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3L3Z","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ZQT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4HLW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4K7A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OEA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OED","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OEY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OEZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OFR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OFU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5JJM","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI2
Number of Residues2
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"15563469","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16641486","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17591767","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25091737","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1T5Z","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1T63","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1T65","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1XJ7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2AM9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2AMA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PIO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PIP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PIQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PIR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PIT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PIU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PIV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PIW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PIX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PKL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2Q7I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2Q7J","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2Q7K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2Q7L","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2YHD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2YLO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2YLP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2YLQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2Z4J","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3L3X","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3L3Z","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ZQT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4HLW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4K7A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OEA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OED","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OEY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OEZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OFR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OFU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5JJM","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI3
Number of Residues1
DetailsSite: {"description":"Interaction with coactivator LXXL and FXXFY motifs","evidences":[{"source":"PubMed","id":"25091737","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI4
Number of Residues1
DetailsSite: {"description":"Interaction with coactivator FXXLF and FXXFY motifs","evidences":[{"source":"PubMed","id":"25091737","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI5
Number of Residues1
DetailsModified residue: {"description":"Phosphotyrosine; by CSK","evidences":[{"source":"PubMed","id":"17045208","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

243531

PDB entries from 2025-10-22

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