2Q4V
Ensemble refinement of the protein crystal structure of thialysine n-acetyltransferase (SSAT2) from Homo sapiens
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004145 | molecular_function | diamine N-acetyltransferase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006596 | biological_process | polyamine biosynthetic process |
| A | 0008080 | molecular_function | N-acetyltransferase activity |
| A | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| A | 0032918 | biological_process | spermidine acetylation |
| A | 0032919 | biological_process | spermine acetylation |
| A | 0032920 | biological_process | putrescine acetylation |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0046204 | biological_process | nor-spermidine metabolic process |
| A | 0070062 | cellular_component | extracellular exosome |
| B | 0004145 | molecular_function | diamine N-acetyltransferase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006596 | biological_process | polyamine biosynthetic process |
| B | 0008080 | molecular_function | N-acetyltransferase activity |
| B | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| B | 0032918 | biological_process | spermidine acetylation |
| B | 0032919 | biological_process | spermine acetylation |
| B | 0032920 | biological_process | putrescine acetylation |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0046204 | biological_process | nor-spermidine metabolic process |
| B | 0070062 | cellular_component | extracellular exosome |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE ACO A 306 |
| Chain | Residue |
| A | LEU24 |
| A | GLY102 |
| A | GLN103 |
| A | GLY104 |
| A | GLY106 |
| A | SER107 |
| A | LEU127 |
| A | ALA128 |
| A | ASN133 |
| A | ARG135 |
| A | LEU139 |
| A | PHE27 |
| A | TYR140 |
| A | HOH311 |
| A | HOH314 |
| A | HOH320 |
| A | HOH364 |
| B | ARG101 |
| B | GLY102 |
| B | ARG135 |
| B | HOH190 |
| B | HOH322 |
| A | LEU91 |
| A | GLU92 |
| A | ASP93 |
| A | ILE94 |
| A | TYR95 |
| A | VAL96 |
| A | ARG101 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"UniProtKB","id":"P0A951","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P21673","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 20 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16596569","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
