2Q1Y

Crystal Structure of cell division protein FtsZ from Mycobacterium tuberculosis in complex with GTP-gamma-S

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0000287	molecular_function	magnesium ion binding
A	0000917	biological_process	division septum assembly
A	0000921	biological_process	septin ring assembly
A	0003924	molecular_function	GTPase activity
A	0005515	molecular_function	protein binding
A	0005525	molecular_function	GTP binding
A	0005737	cellular_component	cytoplasm
A	0005886	cellular_component	plasma membrane
A	0032153	cellular_component	cell division site
A	0043093	biological_process	FtsZ-dependent cytokinesis
A	0045787	biological_process	positive regulation of cell cycle
A	0051258	biological_process	protein polymerization
A	0051301	biological_process	cell division
A	0090529	biological_process	cell septum assembly
B	0000166	molecular_function	nucleotide binding
B	0000287	molecular_function	magnesium ion binding
B	0000917	biological_process	division septum assembly
B	0000921	biological_process	septin ring assembly
B	0003924	molecular_function	GTPase activity
B	0005515	molecular_function	protein binding
B	0005525	molecular_function	GTP binding
B	0005737	cellular_component	cytoplasm
B	0005886	cellular_component	plasma membrane
B	0032153	cellular_component	cell division site
B	0043093	biological_process	FtsZ-dependent cytokinesis
B	0045787	biological_process	positive regulation of cell cycle
B	0051258	biological_process	protein polymerization
B	0051301	biological_process	cell division
B	0090529	biological_process	cell septum assembly

Functional Information from PDB Data

site_id	AC1
Number of Residues	28
Details	BINDING SITE FOR RESIDUE GSP A 401

Chain	Residue
A	GLY17
A	GLY101
A	GLY104
A	GLY105
A	THR106
A	GLY107
A	PRO132
A	GLU136
A	ARG140
A	PHE180
A	ALA183
A	GLY18
A	ASP184
A	HOH402
A	HOH404
A	HOH415
A	HOH420
A	HOH429
A	HOH434
A	HOH443
A	HOH446
A	GLY19
A	ASN22
A	THR42
A	GLY67
A	ALA68
A	GLY69
A	ALA70

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Functional Information from PROSITE/UniProt

site_id	PS01134
Number of Residues	35
Details	FTSZ_1 FtsZ protein signature 1. NTDaQaLlmsdadvkldvgrdstr.GlGAGAdPevG

Chain	Residue	Details
A	ASN41-GLY75

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site_id	PS01135
Number of Residues	22
Details	FTSZ_2 FtsZ protein signature 2. DMvFVTAGeGGGTGTGGAPVVA

Chain	Residue	Details
A	ASP94-ALA115

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	18
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00909","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"15342249","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23888039","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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