2Q1X

Crystal Structure of cell division protein FtsZ from Mycobacterium tuberculosis in complex with citrate.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0000287	molecular_function	magnesium ion binding
A	0000917	biological_process	division septum assembly
A	0000921	biological_process	septin ring assembly
A	0003924	molecular_function	GTPase activity
A	0005515	molecular_function	protein binding
A	0005525	molecular_function	GTP binding
A	0005737	cellular_component	cytoplasm
A	0005886	cellular_component	plasma membrane
A	0032153	cellular_component	cell division site
A	0043093	biological_process	FtsZ-dependent cytokinesis
A	0045787	biological_process	positive regulation of cell cycle
A	0051258	biological_process	protein polymerization
A	0051301	biological_process	cell division
A	0090529	biological_process	cell septum assembly
B	0000166	molecular_function	nucleotide binding
B	0000287	molecular_function	magnesium ion binding
B	0000917	biological_process	division septum assembly
B	0000921	biological_process	septin ring assembly
B	0003924	molecular_function	GTPase activity
B	0005515	molecular_function	protein binding
B	0005525	molecular_function	GTP binding
B	0005737	cellular_component	cytoplasm
B	0005886	cellular_component	plasma membrane
B	0032153	cellular_component	cell division site
B	0043093	biological_process	FtsZ-dependent cytokinesis
B	0045787	biological_process	positive regulation of cell cycle
B	0051258	biological_process	protein polymerization
B	0051301	biological_process	cell division
B	0090529	biological_process	cell septum assembly

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	BINDING SITE FOR RESIDUE CIT A 501

Chain	Residue
A	GLY17
A	HOH502
A	HOH504
A	HOH526
A	HOH546
A	GLY18
A	GLY19
A	ASN41
A	GLY101
A	GLY104
A	GLY105
A	THR106
A	GLY107

---

Functional Information from PROSITE/UniProt

site_id	PS01134
Number of Residues	35
Details	FTSZ_1 FtsZ protein signature 1. NTDaQaLlmsdadvkldvgrdstr.GlGAGAdPevG

Chain	Residue	Details
A	ASN41-GLY75

---

site_id	PS01135
Number of Residues	22
Details	FTSZ_2 FtsZ protein signature 2. DMvFVTAGeGGGTGTGGAPVVA

Chain	Residue	Details
A	ASP94-ALA115

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	17
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00909","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"15342249","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23888039","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---