Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0006027 | biological_process | glycosaminoglycan catabolic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0030246 | molecular_function | carbohydrate binding |
| A | 0034000 | molecular_function | chondroitin-sulfate-ABC endolyase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0006027 | biological_process | glycosaminoglycan catabolic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0030246 | molecular_function | carbohydrate binding |
| B | 0034000 | molecular_function | chondroitin-sulfate-ABC endolyase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA A 2001 |
| Chain | Residue |
| A | SER24 |
| A | GLU26 |
| A | ASP50 |
| A | HIS53 |
| A | ASP161 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PO4 A 2002 |
| Chain | Residue |
| A | TYR336 |
| A | ARG375 |
| A | ARG378 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PO4 A 2003 |
| Chain | Residue |
| A | ALA310 |
| A | GLY311 |
| A | ARG315 |
| A | TYR305 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PO4 A 2004 |
| Chain | Residue |
| A | THR241 |
| A | LYS245 |
| A | ARG300 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 A 2005 |
| Chain | Residue |
| A | ILE745 |
| A | ASP746 |
| A | GLY747 |
| A | MSE748 |
| A | ASP885 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PO4 A 2006 |
| Chain | Residue |
| A | SER1007 |
| A | TYR1008 |
| A | HOH2041 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PO4 A 2007 |
| Chain | Residue |
| A | TYR253 |
| A | GLU585 |
| A | ASN586 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PO4 A 2008 |
| Chain | Residue |
| A | HIS190 |
| A | TRP191 |
| A | HIS345 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PO4 A 2009 |
| Chain | Residue |
| A | ARG267 |
| A | LYS281 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA B 2002 |
| Chain | Residue |
| B | SER24 |
| B | GLU26 |
| B | ASP50 |
| B | HIS53 |
| B | ASP161 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PO4 B 2003 |
| Chain | Residue |
| B | TYR336 |
| B | ARG375 |
| B | ARG378 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PO4 B 2004 |
| Chain | Residue |
| B | TYR305 |
| B | ALA310 |
| B | GLY311 |
| B | ARG315 |
| site_id | BC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PO4 B 2005 |
| Chain | Residue |
| B | LYS245 |
| B | ARG300 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PO4 B 2006 |
| Chain | Residue |
| B | TYR630 |
| B | GLY698 |
| B | MSE699 |
| B | GLU700 |
| site_id | BC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PO4 B 2007 |
| Chain | Residue |
| B | ARG267 |
| B | LYS281 |
| site_id | BC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PO4 B 2008 |
| Chain | Residue |
| B | HIS190 |
| B | TRP191 |
| B | HIS345 |
| site_id | BC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PO4 B 2009 |
| Chain | Residue |
| B | TYR461 |
| B | ARG514 |
| B | HIS515 |
| site_id | BC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PO4 B 2010 |
| Chain | Residue |
| B | HIS453 |
| B | HIS454 |
| B | TYR461 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"UniProtKB","id":"C5G6D7","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"UniProtKB","id":"C5G6D7","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"C5G6D7","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Site: {"description":"Important for catalytic activity against all substrates","evidences":[{"source":"UniProtKB","id":"C5G6D7","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Site: {"description":"Important for catalytic activity against dermatan sulfate substrate","evidences":[{"source":"UniProtKB","id":"C5G6D7","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Site: {"description":"Transition state stabilizer","evidences":[{"source":"UniProtKB","id":"C5G6D7","evidenceCode":"ECO:0000250"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1c82 |
| Chain | Residue | Details |
| A | ASN401 | |
| A | HIS454 | |
| A | TYR461 | |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1c82 |
| Chain | Residue | Details |
| B | ASN401 | |
| B | HIS454 | |
| B | TYR461 | |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1c82 |
| Chain | Residue | Details |
| A | ARG514 | |
| A | HIS454 | |
| A | TYR461 | |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1c82 |
| Chain | Residue | Details |
| B | ARG514 | |
| B | HIS454 | |
| B | TYR461 | |
