2Q14
Crystal structure of Phosphohydrolase (BT4208) from Bacteroides thetaiotaomicron VPI-5482 at 2.20 A resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0006203 | biological_process | dGTP catabolic process |
| A | 0008832 | molecular_function | dGTPase activity |
| A | 0042558 | biological_process | pteridine-containing compound metabolic process |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0006203 | biological_process | dGTP catabolic process |
| B | 0008832 | molecular_function | dGTPase activity |
| B | 0042558 | biological_process | pteridine-containing compound metabolic process |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0006203 | biological_process | dGTP catabolic process |
| C | 0008832 | molecular_function | dGTPase activity |
| C | 0042558 | biological_process | pteridine-containing compound metabolic process |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0006203 | biological_process | dGTP catabolic process |
| D | 0008832 | molecular_function | dGTPase activity |
| D | 0042558 | biological_process | pteridine-containing compound metabolic process |
| E | 0000166 | molecular_function | nucleotide binding |
| E | 0006203 | biological_process | dGTP catabolic process |
| E | 0008832 | molecular_function | dGTPase activity |
| E | 0042558 | biological_process | pteridine-containing compound metabolic process |
| F | 0000166 | molecular_function | nucleotide binding |
| F | 0006203 | biological_process | dGTP catabolic process |
| F | 0008832 | molecular_function | dGTPase activity |
| F | 0042558 | biological_process | pteridine-containing compound metabolic process |
| G | 0000166 | molecular_function | nucleotide binding |
| G | 0006203 | biological_process | dGTP catabolic process |
| G | 0008832 | molecular_function | dGTPase activity |
| G | 0042558 | biological_process | pteridine-containing compound metabolic process |
| H | 0000166 | molecular_function | nucleotide binding |
| H | 0006203 | biological_process | dGTP catabolic process |
| H | 0008832 | molecular_function | dGTPase activity |
| H | 0042558 | biological_process | pteridine-containing compound metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL D 410 |
| Chain | Residue |
| D | PHE81 |
| D | SER83 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 410 |
| Chain | Residue |
| A | GLY182 |
| A | SER206 |
| A | HOH506 |
| D | THR177 |
| D | GLU178 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE ADP A 501 |
| Chain | Residue |
| A | ARG313 |
| A | HOH762 |
| B | ILE7 |
| B | TYR24 |
| B | GLN33 |
| B | PHE56 |
| A | VAL46 |
| A | THR226 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE ADP B 501 |
| Chain | Residue |
| A | ILE7 |
| A | ILE8 |
| A | TYR24 |
| A | GLN33 |
| B | VAL46 |
| B | VAL47 |
| B | LYS225 |
| B | THR226 |
| B | ARG313 |
| B | HOH714 |
| B | HOH721 |
| B | HOH756 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE ADP C 501 |
| Chain | Residue |
| C | VAL46 |
| C | VAL47 |
| C | THR226 |
| C | ARG313 |
| C | HOH594 |
| C | HOH648 |
| D | ILE7 |
| D | ILE8 |
| D | TYR24 |
| D | GLN33 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE ADP D 501 |
| Chain | Residue |
| A | LYS202 |
| C | ILE7 |
| C | ILE8 |
| C | TYR24 |
| C | GLN33 |
| D | VAL46 |
| D | VAL47 |
| D | THR226 |
| D | ARG313 |
| D | HOH567 |
| site_id | AC7 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE ADP E 501 |
| Chain | Residue |
| E | VAL46 |
| E | VAL47 |
| E | THR226 |
| E | ARG313 |
| E | HOH624 |
| E | HOH701 |
| F | LYS6 |
| F | ILE7 |
| F | TYR24 |
| F | GLN33 |
| F | PHE56 |
| H | LYS202 |
| site_id | AC8 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE ADP F 501 |
| Chain | Residue |
| E | ILE7 |
| E | TYR24 |
| E | ARG28 |
| E | GLN33 |
| F | VAL46 |
| F | VAL47 |
| F | LYS225 |
| F | THR226 |
| F | ARG313 |
| F | HOH657 |
| F | HOH726 |
| F | HOH736 |
| site_id | AC9 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE ADP G 501 |
| Chain | Residue |
| G | VAL46 |
| G | THR226 |
| G | ARG313 |
| G | HOH652 |
| G | HOH653 |
| G | HOH671 |
| H | ILE7 |
| H | GLN33 |
| H | PHE56 |
| site_id | BC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE ADP H 501 |
| Chain | Residue |
| E | LYS202 |
| G | ILE7 |
| G | ILE8 |
| G | TYR24 |
| G | VAL27 |
| G | GLN33 |
| H | VAL46 |
| H | VAL47 |
| H | THR226 |
| H | ARG313 |
| H | HOH557 |
| H | HOH604 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 502 |
| Chain | Residue |
| A | GLN40 |
| A | VAL41 |
| A | ASP170 |
| A | HOH696 |
| site_id | BC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO G 502 |
| Chain | Residue |
| G | GLN40 |
| G | VAL41 |
| G | ASP170 |
| site_id | BC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO E 502 |
| Chain | Residue |
| E | GLN40 |
| E | VAL41 |
| E | ASP170 |
| E | TYR222 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO C 502 |
| Chain | Residue |
| C | GLN40 |
| C | VAL41 |
| C | TYR166 |
| C | ASP170 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO G 503 |
| Chain | Residue |
| G | ARG196 |
| G | LEU197 |
| G | SER368 |
| G | ILE369 |
| G | ASP370 |
| site_id | BC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 503 |
| Chain | Residue |
| A | SER236 |
| A | ASN349 |
| A | VAL352 |
| A | SER353 |
| site_id | BC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL H 502 |
| Chain | Residue |
| H | GLN40 |
| H | TYR166 |
| H | ASP170 |
| H | TYR222 |
| site_id | BC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL D 502 |
| Chain | Residue |
| D | GLN40 |
| D | VAL41 |
| D | TYR166 |
| D | ASP170 |
| D | HOH534 |
| D | HOH664 |
| site_id | CC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 502 |
| Chain | Residue |
| B | GLN40 |
| B | VAL41 |
| B | TYR166 |
| B | ASP170 |
| B | TYR218 |
| B | TYR222 |
| B | HOH576 |
| B | HOH582 |
