2Q09
Crystal structure of Imidazolonepropionase from environmental sample with bound inhibitor 3-(2,5-Dioxo-imidazolidin-4-yl)-propionic acid
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005506 | molecular_function | iron ion binding |
A | 0005737 | cellular_component | cytoplasm |
A | 0006547 | biological_process | L-histidine metabolic process |
A | 0006548 | biological_process | L-histidine catabolic process |
A | 0008270 | molecular_function | zinc ion binding |
A | 0016787 | molecular_function | hydrolase activity |
A | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
A | 0016812 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides |
A | 0019556 | biological_process | L-histidine catabolic process to glutamate and formamide |
A | 0019557 | biological_process | L-histidine catabolic process to glutamate and formate |
A | 0046872 | molecular_function | metal ion binding |
A | 0050480 | molecular_function | imidazolonepropionase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE FE A 500 |
Chain | Residue |
A | HIS72 |
A | HIS74 |
A | HIS242 |
A | ASP317 |
A | HOH859 |
site_id | AC2 |
Number of Residues | 11 |
Details | BINDING SITE FOR RESIDUE DI6 A 600 |
Chain | Residue |
A | HIS242 |
A | GLN245 |
A | ASN319 |
A | GLY321 |
A | THR322 |
A | HOH856 |
A | HOH859 |
A | ARG81 |
A | TYR144 |
A | HIS177 |
A | PHE214 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 7 |
Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00372 |
Chain | Residue | Details |
A | HIS72 | |
A | HIS74 | |
A | TYR144 | |
A | HIS242 | |
A | ASP317 | |
A | ASN319 | |
A | GLY321 |
site_id | SWS_FT_FI2 |
Number of Residues | 4 |
Details | BINDING: BINDING => ECO:0000305|PubMed:18442260, ECO:0007744|PDB:2Q09 |
Chain | Residue | Details |
A | ARG81 | |
A | HIS177 | |
A | GLN245 | |
A | THR322 |