2PVO
Crystal srtucture of the ternary complex between thioredoxin f, ferredoxin, and ferredoxin: thioredoxin reductase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0009055 | molecular_function | electron transfer activity |
| A | 0015979 | biological_process | photosynthesis |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016730 | molecular_function | oxidoreductase activity, acting on iron-sulfur proteins as donors |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051536 | molecular_function | iron-sulfur cluster binding |
| A | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| A | 0103012 | molecular_function | ferredoxin-thioredoxin reductase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0015979 | biological_process | photosynthesis |
| B | 0016491 | molecular_function | oxidoreductase activity |
| C | 0015035 | molecular_function | protein-disulfide reductase activity |
| D | 0005515 | molecular_function | protein binding |
| D | 0009055 | molecular_function | electron transfer activity |
| D | 0022900 | biological_process | electron transport chain |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0051536 | molecular_function | iron-sulfur cluster binding |
| D | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 201 |
| Chain | Residue |
| A | ARG80 |
| B | LYS62 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 202 |
| Chain | Residue |
| A | LEU50 |
| A | GLY51 |
| A | SER52 |
| D | GLU34 |
| D | PRO36 |
| D | TYR37 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SF4 A 300 |
| Chain | Residue |
| A | CYS74 |
| A | CYS76 |
| A | MET79 |
| A | CYS85 |
| A | HIS86 |
| A | CYS87 |
| A | PHE90 |
| A | CYS55 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE FES D 400 |
| Chain | Residue |
| D | SER38 |
| D | CYS39 |
| D | ARG40 |
| D | GLY42 |
| D | ALA43 |
| D | CYS44 |
| D | CYS47 |
| D | CYS77 |
Functional Information from PROSITE/UniProt
| site_id | PS00197 |
| Number of Residues | 9 |
| Details | 2FE2S_FER_1 2Fe-2S ferredoxin-type iron-sulfur binding region signature. CRAGACSTC |
| Chain | Residue | Details |
| D | CYS39-CYS47 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00465, ECO:0000269|PubMed:7578051 |
| Chain | Residue | Details |
| D | CYS39 | |
| D | CYS44 | |
| D | CYS47 | |
| D | CYS77 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | SITE: Deprotonates C-terminal active site Cys |
| Chain | Residue | Details |
| C | ASP40 | |
| A | CYS74 | |
| A | CYS76 | |
| A | CYS85 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | SITE: Contributes to redox potential value |
| Chain | Residue | Details |
| C | GLY47 | |
| C | PRO48 |
