2PUO
Crystal srtucture of the NEM modified ferredoxin:thioredoxin reductase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0009055 | molecular_function | electron transfer activity |
| A | 0015979 | biological_process | photosynthesis |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016730 | molecular_function | oxidoreductase activity, acting on iron-sulfur proteins as donors |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051536 | molecular_function | iron-sulfur cluster binding |
| A | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| A | 0103012 | molecular_function | ferredoxin-thioredoxin reductase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0015979 | biological_process | photosynthesis |
| B | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 201 |
| Chain | Residue |
| A | ARG80 |
| A | HOH332 |
| A | HOH352 |
| B | LYS62 |
| B | HIS64 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SF4 A 202 |
| Chain | Residue |
| A | CYS85 |
| A | HIS86 |
| A | CYS87 |
| A | CYS55 |
| A | CYS74 |
| A | CYS76 |
| A | MET79 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NEQ A 301 |
| Chain | Residue |
| A | VAL35 |
| A | CYS57 |
| A | CYS87 |
| B | MET1 |
| B | ASN2 |
| B | VAL38 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"10649999","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14769790","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17611542","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19132843","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10649999","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17611542","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Site: {"description":"Increases the nucleophilicity of the active site Cys","evidences":[{"source":"PubMed","id":"19132843","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | Region: {"description":"Interaction with ferredoxin","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
