Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000413 | biological_process | protein peptidyl-prolyl isomerization |
| A | 0003755 | molecular_function | peptidyl-prolyl cis-trans isomerase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006457 | biological_process | protein folding |
| A | 0016018 | molecular_function | cyclosporin A binding |
| A | 0016853 | molecular_function | isomerase activity |
| B | 0000413 | biological_process | protein peptidyl-prolyl isomerization |
| B | 0003755 | molecular_function | peptidyl-prolyl cis-trans isomerase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006457 | biological_process | protein folding |
| B | 0016018 | molecular_function | cyclosporin A binding |
| B | 0016853 | molecular_function | isomerase activity |
| C | 0000413 | biological_process | protein peptidyl-prolyl isomerization |
| C | 0003755 | molecular_function | peptidyl-prolyl cis-trans isomerase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006457 | biological_process | protein folding |
| C | 0016018 | molecular_function | cyclosporin A binding |
| C | 0016853 | molecular_function | isomerase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR CHAIN T OF CYCLOSPORIN A |
| Chain | Residue |
| A | ARG78 |
| A | TRP144 |
| A | HIS149 |
| B | GLN30 |
| C | LYS167 |
| C | CYS168 |
| C | THR176 |
| T | HOH2001 |
| T | HOH2002 |
| T | HOH2003 |
| T | HOH2004 |
| A | PHE83 |
| A | GLN86 |
| A | GLY95 |
| A | ALA124 |
| A | ASN125 |
| A | ALA126 |
| A | GLN134 |
| A | PHE136 |
| site_id | AC2 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR CHAIN U OF CYCLOSPORIN A |
| Chain | Residue |
| B | TYR15 |
| B | PHE16 |
| B | VAL21 |
| B | ARG78 |
| B | PHE83 |
| B | GLN86 |
| B | GLY95 |
| B | ALA124 |
| B | ASN125 |
| B | ALA126 |
| B | GLN134 |
| B | PHE136 |
| B | TRP144 |
| B | LEU145 |
| B | HIS149 |
| B | GLU157 |
| B | VAL186 |
| B | HOH2017 |
| B | HOH2036 |
| B | HOH2039 |
| B | HOH2077 |
| U | HOH2001 |
| U | HOH2002 |
| V | MLE3 |
| V | MLE10 |
| V | ALA11 |
| site_id | AC3 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR CHAIN V OF CYCLOSPORIN A |
| Chain | Residue |
| B | TRP144 |
| B | GLU160 |
| C | ARG78 |
| C | PHE83 |
| C | GLN86 |
| C | GLY95 |
| C | ALA124 |
| C | ASN125 |
| C | ALA126 |
| C | GLN134 |
| C | PHE136 |
| C | TRP144 |
| C | LEU145 |
| C | HIS149 |
| U | DAL1 |
| U | MLE2 |
| U | ALA11 |
| V | HOH2001 |
| V | HOH2002 |
| V | HOH2003 |
Functional Information from PROSITE/UniProt
| site_id | PS00170 |
| Number of Residues | 18 |
| Details | CSA_PPIASE_1 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. YtgSfFHRIIpqFMiQGG |
| Chain | Residue | Details |
| A | TYR71-GLY88 | |
