Functional Information from GO Data
| Chain | GOid | namespace | contents |
| X | 0000165 | biological_process | MAPK cascade |
| X | 0000166 | molecular_function | nucleotide binding |
| X | 0004672 | molecular_function | protein kinase activity |
| X | 0004708 | molecular_function | MAP kinase kinase activity |
| X | 0005524 | molecular_function | ATP binding |
| X | 0006468 | biological_process | protein phosphorylation |
| X | 0016301 | molecular_function | kinase activity |
| X | 0016740 | molecular_function | transferase activity |
| X | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MN X 383 |
| Chain | Residue |
| X | LYS174 |
| X | ASN177 |
| X | ASP190 |
| X | ANP381 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE ANP X 381 |
| Chain | Residue |
| X | LEU101 |
| X | GLU118 |
| X | TYR119 |
| X | MET120 |
| X | ASP123 |
| X | LYS174 |
| X | SER176 |
| X | ASN177 |
| X | LEU179 |
| X | ASP190 |
| X | MN383 |
| X | HOH401 |
| X | ASN35 |
| X | ASN40 |
| X | ILE42 |
| X | ALA53 |
| X | LYS55 |
Functional Information from PROSITE/UniProt
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. IcHrDVKpsNILM |
| Chain | Residue | Details |
| X | ILE168-MET180 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| X | ASP172 | |
| X | SER176 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| X | ASP172 | |
| X | LYS174 | |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| X | ASP172 | |
| X | THR208 | |
| X | LYS174 | |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| X | ASP172 | |
| X | ASN177 | |
| X | LYS174 | |
