Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004798 | molecular_function | dTMP kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006227 | biological_process | dUDP biosynthetic process |
| A | 0006233 | biological_process | dTDP biosynthetic process |
| A | 0006235 | biological_process | dTTP biosynthetic process |
| A | 0009165 | biological_process | nucleotide biosynthetic process |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016740 | molecular_function | transferase activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004798 | molecular_function | dTMP kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006227 | biological_process | dUDP biosynthetic process |
| B | 0006233 | biological_process | dTDP biosynthetic process |
| B | 0006235 | biological_process | dTTP biosynthetic process |
| B | 0009165 | biological_process | nucleotide biosynthetic process |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016740 | molecular_function | transferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 214 |
| Chain | Residue |
| A | ASP13 |
| A | ARG93 |
| A | GLN169 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 215 |
| Chain | Residue |
| A | ARG101 |
| A | TYR168 |
| A | HOH2112 |
| A | HOH2185 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PO4 A 1901 |
| Chain | Residue |
| A | SER15 |
| A | GLY16 |
| A | LYS17 |
| A | SER18 |
| A | HOH2049 |
| A | HOH2094 |
| A | HOH2097 |
| A | ASP13 |
| A | GLY14 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 1PE B 1301 |
| Chain | Residue |
| A | LYS113 |
| A | ASP182 |
| A | HOH2003 |
| B | ILE109 |
| B | LEU159 |
| B | LYS178 |
| B | HOH1619 |
| B | HOH1633 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 1PE A 1302 |
| Chain | Residue |
| A | LYS114 |
| A | SER117 |
| A | HOH2006 |
| A | HOH2023 |
| B | TRP111 |
| B | LYS114 |
| B | GLU174 |
| B | HOH1649 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE 1PE B 1303 |
| Chain | Residue |
| B | ASP110 |
| B | LYS114 |
| B | ILE155 |
| B | PHE156 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PGE A 1401 |
| Chain | Residue |
| A | SER103 |
| A | GLU174 |
| A | LYS178 |
| B | GLY158 |
| B | LEU159 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PGE A 1402 |
| Chain | Residue |
| A | ASP177 |
| A | HOH2138 |
| B | PRO157 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PGE A 1404 |
| Chain | Residue |
| A | LYS140 |
| A | LYS203 |
| A | PHE204 |
| A | GLU207 |
| A | HOH2200 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 1501 |
| Chain | Residue |
| A | GLU29 |
| A | LYS31 |
| A | ARG32 |
| site_id | BC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO B 1502 |
| Chain | Residue |
| B | SER117 |
| B | ALA119 |
| site_id | BC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO B 1503 |
| Chain | Residue |
| B | LYS55 |
| B | HOH1626 |
| site_id | BC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO A 1504 |
| Chain | Residue |
| A | ARG77 |
| A | HOH2017 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 1505 |
| Chain | Residue |
| A | TRP27 |
| A | LYS31 |
| A | ASP47 |
| A | HOH2197 |
| site_id | BC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PG4 B 1601 |
| Chain | Residue |
| A | LYS121 |
| A | GLU183 |
| A | HOH1982 |
| B | ARG129 |
| B | ASP177 |
| B | HOH1719 |
| B | HOH1806 |
| site_id | BC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE DTT A 1701 |
| Chain | Residue |
| A | PRO60 |
| A | PHE63 |
| A | HIS67 |
| A | ASP102 |
| A | ARG105 |
| A | ASP154 |
| A | HOH2134 |
| site_id | BC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EPE A 1801 |
| Chain | Residue |
| A | TYR35 |
| A | THR37 |
| A | SER41 |
| A | SER42 |
| A | ASP43 |
| A | ARG74 |
| A | TYR78 |
| A | HOH2179 |
| site_id | BC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PEG A 1201 |
| Chain | Residue |
| A | TRP39 |
| A | HIS67 |
| A | ASP70 |
| A | ARG74 |
| A | HOH2037 |
| A | HOH2041 |
| site_id | CC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG A 1202 |
| Chain | Residue |
| A | ASP108 |
| A | TRP111 |
| A | HOH2000 |
| A | HOH2180 |
| B | PHE118 |
| site_id | CC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG B 1203 |
| Chain | Residue |
| B | HOH1733 |
| A | SER117 |
| B | ASP108 |
| B | TRP111 |
| B | HOH1728 |
| site_id | CC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PEG A 1204 |
| Chain | Residue |
| A | GLY14 |
| A | ARG138 |
| site_id | CC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PEG A 1206 |
| Chain | Residue |
| A | ARG129 |
| A | ASP177 |
| A | HOH1913 |
| site_id | CC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PEG A 1207 |
| Chain | Residue |
| A | HOH2131 |
| A | HOH2196 |
| A | HOH2206 |
| site_id | CC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PEG A 1208 |
| Chain | Residue |
| A | ASN184 |
| A | ILE186 |
| A | HOH2034 |
| B | LYS181 |
| B | HOH1709 |
| B | HOH1800 |
| site_id | CC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PEG B 1209 |
| Chain | Residue |
| A | ARG129 |
| A | SER131 |
| A | PRO132 |
| A | THR173 |
| B | LYS53 |
| B | LYS54 |
| B | ASP56 |
| site_id | CC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PEG B 1210 |
| Chain | Residue |
| B | LEU58 |
| B | ASP154 |
| site_id | CC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PEG B 1211 |
| Chain | Residue |
| A | HOH2021 |
| B | LEU136 |
| B | LYS140 |
| B | GLU162 |
| B | GLU163 |
| B | LEU166 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]} |
