2PL5

Crystal Structure of Homoserine O-acetyltransferase from Leptospira interrogans

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004414	molecular_function	homoserine O-acetyltransferase activity
A	0005737	cellular_component	cytoplasm
A	0008652	biological_process	amino acid biosynthetic process
A	0009058	biological_process	biosynthetic process
A	0009086	biological_process	methionine biosynthetic process
A	0016740	molecular_function	transferase activity
A	0016746	molecular_function	acyltransferase activity
A	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL A 400

Chain	Residue
A	GLY100
A	CYS101
A	LYS102
A	GLY103
A	SER104
A	GLY106
A	PRO107
A	LEU108
A	SER109

---

site_id	AC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL A 500

Chain	Residue
A	LEU28
A	SER29
A	PRO30
A	SER105
A	SER109
A	TYR118
A	HOH507
A	HOH540
A	HOH577

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	302
Details	Domain: {"description":"AB hydrolase-1","evidences":[{"source":"HAMAP-Rule","id":"MF_00296","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"HAMAP-Rule","id":"MF_00296","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17927957","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00296","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17927957","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00296","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	3
Details	Annotated By Reference To The Literature 1azw

Chain	Residue	Details
A	ASP311
A	HIS344
A	SER153

---