2PIA

PHTHALATE DIOXYGENASE REDUCTASE: A MODULAR STRUCTURE FOR ELECTRON TRANSFER FROM PYRIDINE NUCLEOTIDES TO [2FE-2S]

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016491	molecular_function	oxidoreductase activity
A	0051536	molecular_function	iron-sulfur cluster binding
A	0051537	molecular_function	2 iron, 2 sulfur cluster binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	23
Details	BINDING SITE FOR RESIDUE FMN A 322

Chain	Residue
A	ASN44
A	ARG80
A	GLY82
A	SER83
A	ILE121
A	THR124
A	GLU223
A	PHE225
A	SER274
A	HOH327
A	HOH329
A	ARG55
A	HOH331
A	HOH332
A	HOH354
A	HOH368
A	THR56
A	TYR57
A	SER58
A	ALA72
A	VAL73
A	LYS74
A	GLY79

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site_id	AC2
Number of Residues	10
Details	BINDING SITE FOR RESIDUE FES A 323

Chain	Residue
A	SER271
A	CYS272
A	GLU273
A	GLY275
A	THR276
A	CYS277
A	GLY278
A	CYS280
A	MET306
A	CYS308

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Functional Information from PROSITE/UniProt

site_id	PS00197
Number of Residues	9
Details	2FE2S_FER_1 2Fe-2S ferredoxin-type iron-sulfur binding region signature. CESGTCGSC

Chain	Residue	Details
A	CYS272-CYS280

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	102
Details	Domain: {"description":"FAD-binding FR-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00716","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	83
Details	Domain: {"description":"2Fe-2S ferredoxin-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00465","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	13
Details	Binding site: {"evidences":[{"source":"PubMed","id":"1280857","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2PIA","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	4
Details	a catalytic site defined by CSA, PubMed 1280857

Chain	Residue	Details
A	CYS199
A	ASN44
A	SER58
A	GLU223

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