2PH9

Galanthamine bound to an ACh-binding Protein

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004888	molecular_function	transmembrane signaling receptor activity
A	0005216	molecular_function	monoatomic ion channel activity
A	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
A	0006811	biological_process	monoatomic ion transport
A	0016020	cellular_component	membrane
A	0034220	biological_process	monoatomic ion transmembrane transport
B	0004888	molecular_function	transmembrane signaling receptor activity
B	0005216	molecular_function	monoatomic ion channel activity
B	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
B	0006811	biological_process	monoatomic ion transport
B	0016020	cellular_component	membrane
B	0034220	biological_process	monoatomic ion transmembrane transport
C	0004888	molecular_function	transmembrane signaling receptor activity
C	0005216	molecular_function	monoatomic ion channel activity
C	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
C	0006811	biological_process	monoatomic ion transport
C	0016020	cellular_component	membrane
C	0034220	biological_process	monoatomic ion transmembrane transport
D	0004888	molecular_function	transmembrane signaling receptor activity
D	0005216	molecular_function	monoatomic ion channel activity
D	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
D	0006811	biological_process	monoatomic ion transport
D	0016020	cellular_component	membrane
D	0034220	biological_process	monoatomic ion transmembrane transport
E	0004888	molecular_function	transmembrane signaling receptor activity
E	0005216	molecular_function	monoatomic ion channel activity
E	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
E	0006811	biological_process	monoatomic ion transport
E	0016020	cellular_component	membrane
E	0034220	biological_process	monoatomic ion transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GNT A 301

Chain	Residue
A	TYR93
A	TRP147
A	GLN186
A	TYR188
A	TYR195
A	HOH307
B	ILE118

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site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GNT C 301

Chain	Residue
C	CYS190
C	TYR195
C	HOH314
D	TYR55
D	GLN57
D	ILE118
C	TYR93
C	TYR188

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site_id	AC3
Number of Residues	11
Details	BINDING SITE FOR RESIDUE GNT D 301

Chain	Residue
D	TYR93
D	TRP147
D	TYR188
D	CYS190
D	CYS191
D	TYR195
D	HOH313
D	HOH319
E	TYR55
E	GLN57
E	ILE118

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site_id	AC4
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GNT E 301

Chain	Residue
A	TYR55
A	GLN57
A	ILE118
E	TYR93
E	TRP147
E	TYR188
E	TYR195
E	HOH303
E	HOH322

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site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PG4 B 401

Chain	Residue
B	TRP147
B	TYR195
B	HOH419
B	HOH422

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