2PA8
X-Ray Crystal Structure of the D/L Subcomplex of the Sulfolobus Solfataricus RNA polymerase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| D | 0000428 | cellular_component | DNA-directed RNA polymerase complex |
| D | 0003677 | molecular_function | DNA binding |
| D | 0003899 | molecular_function | DNA-directed RNA polymerase activity |
| D | 0005515 | molecular_function | protein binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006351 | biological_process | DNA-templated transcription |
| D | 0016740 | molecular_function | transferase activity |
| D | 0016779 | molecular_function | nucleotidyltransferase activity |
| D | 0034062 | molecular_function | 5'-3' RNA polymerase activity |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0046983 | molecular_function | protein dimerization activity |
| D | 0051536 | molecular_function | iron-sulfur cluster binding |
| D | 0051538 | molecular_function | 3 iron, 4 sulfur cluster binding |
| L | 0000428 | cellular_component | DNA-directed RNA polymerase complex |
| L | 0003677 | molecular_function | DNA binding |
| L | 0003899 | molecular_function | DNA-directed RNA polymerase activity |
| L | 0005515 | molecular_function | protein binding |
| L | 0005737 | cellular_component | cytoplasm |
| L | 0006351 | biological_process | DNA-templated transcription |
| L | 0016740 | molecular_function | transferase activity |
| L | 0016779 | molecular_function | nucleotidyltransferase activity |
| L | 0034062 | molecular_function | 5'-3' RNA polymerase activity |
| L | 0046983 | molecular_function | protein dimerization activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 D 400 |
| Chain | Residue |
| D | ARG29 |
| D | HIS153 |
| D | ALA154 |
| D | HOH3091 |
| D | HOH3104 |
| L | HIS22 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE F3S D 3076 |
| Chain | Residue |
| D | CYS203 |
| D | THR204 |
| D | LEU205 |
| D | CYS206 |
| D | GLU207 |
| D | GLU208 |
| D | CYS209 |
| D | ILE219 |
| D | CYS183 |
| D | VAL187 |
| D | PHE188 |
Functional Information from PROSITE/UniProt
| site_id | PS00446 |
| Number of Residues | 41 |
| Details | RNA_POL_D_30KD RNA polymerases D / 30 to 40 Kd subunits signature. NAIRRasmlyvpimAvddVyfieNnSplyDEiLAhRLALIP |
| Chain | Residue | Details |
| D | ASN26-PRO66 |
| site_id | PS01154 |
| Number of Residues | 32 |
| Details | RNA_POL_L_13KD RNA polymerases L / 13 to 16 Kd subunits signature. IegEdHTLgNlIagtLrrisgVsfasYyqpHP |
| Chain | Residue | Details |
| L | ILE17-PRO48 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"18235446","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00320","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"18235446","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2PA8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PMZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3HKZ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00320","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"18235446","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2PA8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3HKZ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
