2P99

E. coli methionine aminopeptidase monometalated with inhibitor YE6

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004177	molecular_function	aminopeptidase activity
A	0004239	molecular_function	initiator methionyl aminopeptidase activity
A	0005829	cellular_component	cytosol
A	0006508	biological_process	proteolysis
A	0008198	molecular_function	ferrous iron binding
A	0008235	molecular_function	metalloexopeptidase activity
A	0046872	molecular_function	metal ion binding
A	0046914	molecular_function	transition metal ion binding
A	0070006	molecular_function	metalloaminopeptidase activity

Functional Information from PROSITE/UniProt

site_id	PS00680
Number of Residues	19
Details	MAP_1 Methionine aminopeptidase subfamily 1 signature. YcGHGIGrgfHeepqVl.HY

Chain	Residue	Details
A	TYR168-TYR186

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01974, ECO:0000269|PubMed:10555963, ECO:0000269|PubMed:16769889, ECO:0000269|PubMed:17120228

Chain	Residue	Details
A	HIS178
A	HIS79

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site_id	SWS_FT_FI2
Number of Residues	5
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01974, ECO:0000269|PubMed:10387007, ECO:0000269|PubMed:10555963, ECO:0000269|PubMed:16769889, ECO:0000269|PubMed:17120228, ECO:0000269|PubMed:18093325, ECO:0000269|PubMed:18785729

Chain	Residue	Details
A	GLU204
A	GLU235
A	ASP97
A	ASP108
A	HIS171

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site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:10555963, ECO:0000269|PubMed:16769889, ECO:0000269|PubMed:17120228

Chain	Residue	Details
A	THR99

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