2P88
Crystal structure of N-succinyl Arg/Lys racemase from Bacillus cereus ATCC 14579
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0006518 | biological_process | peptide metabolic process |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0016854 | molecular_function | racemase and epimerase activity |
| A | 0016855 | molecular_function | racemase and epimerase activity, acting on amino acids and derivatives |
| A | 0036361 | molecular_function | racemase activity, acting on amino acids and derivatives |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0006518 | biological_process | peptide metabolic process |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0016854 | molecular_function | racemase and epimerase activity |
| B | 0016855 | molecular_function | racemase and epimerase activity, acting on amino acids and derivatives |
| B | 0036361 | molecular_function | racemase activity, acting on amino acids and derivatives |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0000287 | molecular_function | magnesium ion binding |
| C | 0006518 | biological_process | peptide metabolic process |
| C | 0016853 | molecular_function | isomerase activity |
| C | 0016854 | molecular_function | racemase and epimerase activity |
| C | 0016855 | molecular_function | racemase and epimerase activity, acting on amino acids and derivatives |
| C | 0036361 | molecular_function | racemase activity, acting on amino acids and derivatives |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0000287 | molecular_function | magnesium ion binding |
| D | 0006518 | biological_process | peptide metabolic process |
| D | 0016853 | molecular_function | isomerase activity |
| D | 0016854 | molecular_function | racemase and epimerase activity |
| D | 0016855 | molecular_function | racemase and epimerase activity, acting on amino acids and derivatives |
| D | 0036361 | molecular_function | racemase activity, acting on amino acids and derivatives |
| D | 0046872 | molecular_function | metal ion binding |
| E | 0000287 | molecular_function | magnesium ion binding |
| E | 0006518 | biological_process | peptide metabolic process |
| E | 0016853 | molecular_function | isomerase activity |
| E | 0016854 | molecular_function | racemase and epimerase activity |
| E | 0016855 | molecular_function | racemase and epimerase activity, acting on amino acids and derivatives |
| E | 0036361 | molecular_function | racemase activity, acting on amino acids and derivatives |
| E | 0046872 | molecular_function | metal ion binding |
| F | 0000287 | molecular_function | magnesium ion binding |
| F | 0006518 | biological_process | peptide metabolic process |
| F | 0016853 | molecular_function | isomerase activity |
| F | 0016854 | molecular_function | racemase and epimerase activity |
| F | 0016855 | molecular_function | racemase and epimerase activity, acting on amino acids and derivatives |
| F | 0036361 | molecular_function | racemase activity, acting on amino acids and derivatives |
| F | 0046872 | molecular_function | metal ion binding |
| G | 0000287 | molecular_function | magnesium ion binding |
| G | 0006518 | biological_process | peptide metabolic process |
| G | 0016853 | molecular_function | isomerase activity |
| G | 0016854 | molecular_function | racemase and epimerase activity |
| G | 0016855 | molecular_function | racemase and epimerase activity, acting on amino acids and derivatives |
| G | 0036361 | molecular_function | racemase activity, acting on amino acids and derivatives |
| G | 0046872 | molecular_function | metal ion binding |
| H | 0000287 | molecular_function | magnesium ion binding |
| H | 0006518 | biological_process | peptide metabolic process |
| H | 0016853 | molecular_function | isomerase activity |
| H | 0016854 | molecular_function | racemase and epimerase activity |
| H | 0016855 | molecular_function | racemase and epimerase activity, acting on amino acids and derivatives |
| H | 0036361 | molecular_function | racemase activity, acting on amino acids and derivatives |
| H | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 501 |
| Chain | Residue |
| A | ASP191 |
| A | ASN193 |
| A | GLU218 |
| A | ASP243 |
| A | HOH530 |
| A | HOH531 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 501 |
| Chain | Residue |
| B | GLU218 |
| B | ASP243 |
| B | HOH534 |
| B | LYS161 |
| B | LYS163 |
| B | ASP191 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG C 501 |
| Chain | Residue |
| C | LYS161 |
| C | LYS163 |
| C | ASP191 |
| C | GLU218 |
| C | ASP243 |
| C | LYS267 |
| C | HOH541 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG D 501 |
| Chain | Residue |
| D | LYS161 |
| D | LYS163 |
| D | ASP191 |
| D | GLU218 |
| D | ASP243 |
| D | LYS267 |
| D | HOH537 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG E 501 |
| Chain | Residue |
| E | ASP191 |
| E | ASN193 |
| E | GLU218 |
| E | ASP243 |
| E | HOH536 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG F 501 |
| Chain | Residue |
| F | LYS163 |
| F | ASP191 |
| F | ASN193 |
| F | GLU218 |
| F | ASP243 |
| F | HOH545 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG G 501 |
| Chain | Residue |
| G | ASP191 |
| G | ASN193 |
| G | GLU218 |
| G | ASP243 |
| G | HOH547 |
| G | HOH548 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG H 501 |
| Chain | Residue |
| H | ASP191 |
| H | ASN193 |
| H | GLU218 |
| H | ASP243 |
| H | HOH538 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 48 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | TYR26 | |
| B | LYS267 | |
| B | SER295 | |
| B | GLU320 | |
| C | TYR26 | |
| C | ASP51 | |
| C | LYS161 | |
| C | LYS267 | |
| C | SER295 | |
| C | GLU320 | |
| D | TYR26 | |
| A | ASP51 | |
| D | ASP51 | |
| D | LYS161 | |
| D | LYS267 | |
| D | SER295 | |
| D | GLU320 | |
| E | TYR26 | |
| E | ASP51 | |
| E | LYS161 | |
| E | LYS267 | |
| E | SER295 | |
| A | LYS161 | |
| E | GLU320 | |
| F | TYR26 | |
| F | ASP51 | |
| F | LYS161 | |
| F | LYS267 | |
| F | SER295 | |
| F | GLU320 | |
| G | TYR26 | |
| G | ASP51 | |
| G | LYS161 | |
| A | LYS267 | |
| G | LYS267 | |
| G | SER295 | |
| G | GLU320 | |
| H | TYR26 | |
| H | ASP51 | |
| H | LYS161 | |
| H | LYS267 | |
| H | SER295 | |
| H | GLU320 | |
| A | SER295 | |
| A | GLU320 | |
| B | TYR26 | |
| B | ASP51 | |
| B | LYS161 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 24 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:17603539 |
| Chain | Residue | Details |
| A | ASP191 | |
| D | ASP191 | |
| D | GLU218 | |
| D | ASP243 | |
| E | ASP191 | |
| E | GLU218 | |
| E | ASP243 | |
| F | ASP191 | |
| F | GLU218 | |
| F | ASP243 | |
| G | ASP191 | |
| A | GLU218 | |
| G | GLU218 | |
| G | ASP243 | |
| H | ASP191 | |
| H | GLU218 | |
| H | ASP243 | |
| A | ASP243 | |
| B | ASP191 | |
| B | GLU218 | |
| B | ASP243 | |
| C | ASP191 | |
| C | GLU218 | |
| C | ASP243 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1muc |
| Chain | Residue | Details |
| A | GLU320 | |
| A | LYS161 | |
| A | LYS163 |
| site_id | CSA10 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1muc |
| Chain | Residue | Details |
| B | LYS163 | |
| B | LYS267 |
| site_id | CSA11 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1muc |
| Chain | Residue | Details |
| C | LYS163 | |
| C | LYS267 |
| site_id | CSA12 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1muc |
| Chain | Residue | Details |
| D | LYS163 | |
| D | LYS267 |
| site_id | CSA13 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1muc |
| Chain | Residue | Details |
| E | LYS163 | |
| E | LYS267 |
| site_id | CSA14 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1muc |
| Chain | Residue | Details |
| F | LYS163 | |
| F | LYS267 |
| site_id | CSA15 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1muc |
| Chain | Residue | Details |
| G | LYS163 | |
| G | LYS267 |
| site_id | CSA16 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1muc |
| Chain | Residue | Details |
| H | LYS163 | |
| H | LYS267 |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1muc |
| Chain | Residue | Details |
| B | GLU320 | |
| B | LYS161 | |
| B | LYS163 |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1muc |
| Chain | Residue | Details |
| C | GLU320 | |
| C | LYS161 | |
| C | LYS163 |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1muc |
| Chain | Residue | Details |
| D | GLU320 | |
| D | LYS161 | |
| D | LYS163 |
| site_id | CSA5 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1muc |
| Chain | Residue | Details |
| E | GLU320 | |
| E | LYS161 | |
| E | LYS163 |
| site_id | CSA6 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1muc |
| Chain | Residue | Details |
| F | GLU320 | |
| F | LYS161 | |
| F | LYS163 |
| site_id | CSA7 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1muc |
| Chain | Residue | Details |
| G | GLU320 | |
| G | LYS161 | |
| G | LYS163 |
| site_id | CSA8 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1muc |
| Chain | Residue | Details |
| H | GLU320 | |
| H | LYS161 | |
| H | LYS163 |
| site_id | CSA9 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1muc |
| Chain | Residue | Details |
| A | LYS163 | |
| A | LYS267 |
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 958 |
| Chain | Residue | Details |
| A | LYS163 | proton shuttle (general acid/base) |
| A | ASP191 | metal ligand |
| A | GLU218 | metal ligand |
| A | ASP243 | metal ligand |
| A | LYS267 | proton shuttle (general acid/base) |
| site_id | MCSA2 |
| Number of Residues | 5 |
| Details | M-CSA 958 |
| Chain | Residue | Details |
| B | LYS163 | proton shuttle (general acid/base) |
| B | ASP191 | metal ligand |
| B | GLU218 | metal ligand |
| B | ASP243 | metal ligand |
| B | LYS267 | proton shuttle (general acid/base) |
| site_id | MCSA3 |
| Number of Residues | 5 |
| Details | M-CSA 958 |
| Chain | Residue | Details |
| C | LYS163 | proton shuttle (general acid/base) |
| C | ASP191 | metal ligand |
| C | GLU218 | metal ligand |
| C | ASP243 | metal ligand |
| C | LYS267 | proton shuttle (general acid/base) |
| site_id | MCSA4 |
| Number of Residues | 5 |
| Details | M-CSA 958 |
| Chain | Residue | Details |
| D | LYS163 | proton shuttle (general acid/base) |
| D | ASP191 | metal ligand |
| D | GLU218 | metal ligand |
| D | ASP243 | metal ligand |
| D | LYS267 | proton shuttle (general acid/base) |
| site_id | MCSA5 |
| Number of Residues | 5 |
| Details | M-CSA 958 |
| Chain | Residue | Details |
| E | LYS163 | proton shuttle (general acid/base) |
| E | ASP191 | metal ligand |
| E | GLU218 | metal ligand |
| E | ASP243 | metal ligand |
| E | LYS267 | proton shuttle (general acid/base) |
| site_id | MCSA6 |
| Number of Residues | 5 |
| Details | M-CSA 958 |
| Chain | Residue | Details |
| F | LYS163 | proton shuttle (general acid/base) |
| F | ASP191 | metal ligand |
| F | GLU218 | metal ligand |
| F | ASP243 | metal ligand |
| F | LYS267 | proton shuttle (general acid/base) |
| site_id | MCSA7 |
| Number of Residues | 5 |
| Details | M-CSA 958 |
| Chain | Residue | Details |
| G | LYS163 | proton shuttle (general acid/base) |
| G | ASP191 | metal ligand |
| G | GLU218 | metal ligand |
| G | ASP243 | metal ligand |
| G | LYS267 | proton shuttle (general acid/base) |
| site_id | MCSA8 |
| Number of Residues | 5 |
| Details | M-CSA 958 |
| Chain | Residue | Details |
| H | LYS163 | proton shuttle (general acid/base) |
| H | ASP191 | metal ligand |
| H | GLU218 | metal ligand |
| H | ASP243 | metal ligand |
| H | LYS267 | proton shuttle (general acid/base) |
