2P7V
Crystal structure of the Escherichia coli regulator of sigma 70, Rsd, in complex with sigma 70 domain 4
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001000 | molecular_function | bacterial-type RNA polymerase core enzyme binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0010468 | biological_process | regulation of gene expression |
| A | 0015968 | biological_process | stringent response |
| A | 0016989 | molecular_function | sigma factor antagonist activity |
| A | 0030813 | biological_process | positive regulation of nucleotide catabolic process |
| A | 0045892 | biological_process | negative regulation of DNA-templated transcription |
| A | 1903865 | cellular_component | sigma factor antagonist complex |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0006352 | biological_process | DNA-templated transcription initiation |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 101 |
| Chain | Residue |
| B | HOH1 |
| B | HOH1 |
| B | GLU605 |
| B | GLU605 |
| B | ARG608 |
| B | ARG608 |
Functional Information from PROSITE/UniProt
| site_id | PS00716 |
| Number of Residues | 27 |
| Details | SIGMA70_2 Sigma-70 factors family signature 2. TleEVGkqfdVTrerIrQIEakaLrkL |
| Chain | Residue | Details |
| B | THR572-LEU598 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 19 |
| Details | Region: {"description":"Interaction with RpoD"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 15 |
| Details | Region: {"description":"Interaction with anti-sigma factors"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Site: {"description":"Interaction with anti-sigma factors"} |
| Chain | Residue | Details |
