Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004164 | molecular_function | diphthine synthase activity |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0017183 | biological_process | protein histidyl modification to diphthamide |
| A | 0032259 | biological_process | methylation |
| B | 0004164 | molecular_function | diphthine synthase activity |
| B | 0008168 | molecular_function | methyltransferase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0017183 | biological_process | protein histidyl modification to diphthamide |
| B | 0032259 | biological_process | methylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE SAH A 1301 |
| Chain | Residue |
| A | LEU10 |
| A | LEU166 |
| A | LEU206 |
| A | ARG208 |
| A | ALA209 |
| A | PRO233 |
| A | HIS234 |
| A | ILE235 |
| A | HOH1322 |
| A | HOH1376 |
| A | HOH1401 |
| A | THR36 |
| A | HOH1434 |
| A | SER37 |
| A | GLY86 |
| A | ASP87 |
| A | VAL90 |
| A | SER115 |
| A | ILE116 |
| A | PHE165 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 401 |
| Chain | Residue |
| B | ASP200 |
| B | TYR220 |
| B | LYS222 |
| B | GLU259 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 402 |
| Chain | Residue |
| B | LEU38 |
| B | MET39 |
| B | THR42 |
| B | THR43 |
| B | ARG173 |
| B | HOH500 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 403 |
| Chain | Residue |
| A | TYR128 |
| B | THR92 |
| B | ALA134 |
| B | THR135 |
| B | HOH458 |
| B | HOH527 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | LEU10 | |
| B | VAL90 | |
| B | SER115 | |
| B | LEU166 | |
| B | ALA209 | |
| B | HIS234 | |
| A | ASP87 | |
| A | VAL90 | |
| A | SER115 | |
| A | LEU166 | |
| A | ALA209 | |
| A | HIS234 | |
| B | LEU10 | |
| B | ASP87 | |
