2P51

Crystal structure of the S. pombe Pop2p deadenylation subunit

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000288	biological_process	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
A	0000289	biological_process	nuclear-transcribed mRNA poly(A) tail shortening
A	0000932	cellular_component	P-body
A	0003676	molecular_function	nucleic acid binding
A	0003682	molecular_function	chromatin binding
A	0003729	molecular_function	mRNA binding
A	0004535	molecular_function	poly(A)-specific ribonuclease activity
A	0004540	molecular_function	RNA nuclease activity
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0008270	molecular_function	zinc ion binding
A	0010629	biological_process	negative regulation of gene expression
A	0030014	cellular_component	CCR4-NOT complex
A	0030015	cellular_component	CCR4-NOT core complex
A	0030145	molecular_function	manganese ion binding
A	0031047	biological_process	regulatory ncRNA-mediated gene silencing
A	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 2001

Chain	Residue
A	ASP50
A	ASP171
A	HOH3001
A	HOH3002
A	HOH3003
A	HOH3004

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 2002

Chain	Residue
A	HOH3005
A	HOH3006
A	HOH3007
A	ASP50
A	GLU52
A	ASP240

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"19307292","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Binding site: {}

Chain

Residue

Details

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