Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004616 | molecular_function | phosphogluconate dehydrogenase (decarboxylating) activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005829 | cellular_component | cytosol |
| A | 0006098 | biological_process | pentose-phosphate shunt |
| A | 0009051 | biological_process | pentose-phosphate shunt, oxidative branch |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019521 | biological_process | D-gluconate metabolic process |
| A | 0034599 | biological_process | cellular response to oxidative stress |
| A | 0050661 | molecular_function | NADP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE FLC A 501 |
| Chain | Residue |
| A | GLU189 |
| A | FLC502 |
| A | TYR190 |
| A | MET193 |
| A | GLN258 |
| A | LYS259 |
| A | THR261 |
| A | ARG286 |
| A | ARG446 |
| A | HIS452 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE FLC A 502 |
| Chain | Residue |
| A | ASN102 |
| A | SER128 |
| A | GLY130 |
| A | LYS182 |
| A | HIS185 |
| A | ASN186 |
| A | GLU189 |
| A | ILE366 |
| A | HIS452 |
| A | FLC501 |
Functional Information from PROSITE/UniProt
| site_id | PS00461 |
| Number of Residues | 13 |
| Details | 6PGD 6-phosphogluconate dehydrogenase signature. ImDtaGQKGTGkW |
| Chain | Residue | Details |
| A | ILE252-TRP264 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 11 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 7 |
| Details | Binding site: {"description":"in other chain","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 2pgd |
| Chain | Residue | Details |
| A | ASN186 | |
| A | GLU189 | |
| A | LYS182 | |
| A | GLY130 | |
2P4Q
