2P40

Crystal Structure of Dengue Methyltransferase in Complex with 7MeGpppG

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003968	molecular_function	RNA-directed RNA polymerase activity
A	0004482	molecular_function	mRNA 5'-cap (guanine-N7-)-methyltransferase activity
A	0004483	molecular_function	methyltransferase cap1 activity
A	0005524	molecular_function	ATP binding
A	0008168	molecular_function	methyltransferase activity
A	0032259	biological_process	methylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 297

Chain	Residue
A	SER230
A	ASN233
A	ARG237

---

site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 298

Chain	Residue
A	SER15
A	ASN18

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 299

Chain	Residue
A	ARG84
A	ARG38
A	LYS42
A	SER56
A	ARG57

---

site_id	AC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 A 300

Chain	Residue
A	GLN34
A	GLU49
A	HIS52
A	HIS53
A	TRP64
A	ARG68
A	PRO209
A	ARG246

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 301

Chain	Residue
A	LYS29
A	LYS30
A	ARG57
A	ARG212

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 302

Chain	Residue
A	LYS105
A	PRO108
A	SER151
A	PRO152
A	ARG160

---

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 303

Chain	Residue
A	LYS105
A	ASP131
A	PHE134
A	ARG160
A	ARG163

---

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 304

Chain	Residue
A	HIS110
A	GLU111
A	HOH322

---

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 305

Chain	Residue
A	LYS12
A	ARG16
A	GLY261
A	THR262
A	HOH348

---

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 306

Chain	Residue
A	ARG57
A	LYS61
A	HOH317
A	HOH336
A	HOH338
A	HOH349

---

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 307

Chain	Residue
A	SER56
A	GLY83
A	ARG84
A	GLU111

---

site_id	BC3
Number of Residues	11
Details	BINDING SITE FOR RESIDUE GTG A 308

Chain	Residue
A	LYS14
A	LEU17
A	ASN18
A	LEU20
A	PHE25
A	LYS29
A	PRO108
A	SER150
A	SER151
A	PRO152
A	SER214

---