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2P31

Crystal structure of human glutathione peroxidase 7

Functional Information from GO Data
ChainGOidnamespacecontents
A0004096molecular_functioncatalase activity
A0004601molecular_functionperoxidase activity
A0004602molecular_functionglutathione peroxidase activity
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005783cellular_componentendoplasmic reticulum
A0005788cellular_componentendoplasmic reticulum lumen
A0006979biological_processresponse to oxidative stress
A0034599biological_processcellular response to oxidative stress
A0098869biological_processcellular oxidant detoxification
B0004096molecular_functioncatalase activity
B0004601molecular_functionperoxidase activity
B0004602molecular_functionglutathione peroxidase activity
B0005515molecular_functionprotein binding
B0005576cellular_componentextracellular region
B0005783cellular_componentendoplasmic reticulum
B0005788cellular_componentendoplasmic reticulum lumen
B0006979biological_processresponse to oxidative stress
B0034599biological_processcellular response to oxidative stress
B0098869biological_processcellular oxidant detoxification
Functional Information from PDB Data
site_idAC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE CL B 201
ChainResidue
BALA30
BVAL31
BHIS126
BARG169
BTHR173

site_idAC2
Number of Residues4
DetailsBINDING SITE FOR RESIDUE CL A 202
ChainResidue
AALA30
AVAL31
AHIS126
ATHR173

Functional Information from PROSITE/UniProt
site_idPS00460
Number of Residues16
DetailsGLUTATHIONE_PEROXID_1 Glutathione peroxidases active site. GSvSLVvNVaSeCGfT
ChainResidueDetails
AGLY45-THR60

site_idPS00763
Number of Residues8
DetailsGLUTATHIONE_PEROXID_2 Glutathione peroxidases signature 2. LAFPCNQF
ChainResidueDetails
ALEU82-PHE89

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsACT_SITE: ACT_SITE => ECO:0000250
ChainResidueDetails
ACYS57
BCYS57

Catalytic Information from CSA
site_idCSA1
Number of Residues2
DetailsAnnotated By Reference To The Literature 1gp1
ChainResidueDetails
ATRP142
AGLN92

site_idCSA2
Number of Residues2
DetailsAnnotated By Reference To The Literature 1gp1
ChainResidueDetails
BTRP142
BGLN92

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PDB entries from 2024-11-06

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