2P2X
Crystal structure of PH0725 from Pyrococcus horikoshii OT3
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004164 | molecular_function | diphthine synthase activity |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0017183 | biological_process | protein histidyl modification to diphthamide |
| A | 0032259 | biological_process | methylation |
| B | 0004164 | molecular_function | diphthine synthase activity |
| B | 0008168 | molecular_function | methyltransferase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0017183 | biological_process | protein histidyl modification to diphthamide |
| B | 0032259 | biological_process | methylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE SAH A 301 |
| Chain | Residue |
| A | LEU10 |
| A | ARG208 |
| A | ALA209 |
| A | PRO233 |
| A | HIS234 |
| A | ILE235 |
| A | HOH314 |
| A | THR36 |
| A | SER37 |
| A | ASP87 |
| A | VAL90 |
| A | SER115 |
| A | ILE116 |
| A | PHE165 |
| A | LEU166 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE SAH A 302 |
| Chain | Residue |
| A | HOH324 |
| A | HOH325 |
| B | SER37 |
| B | ASP87 |
| B | VAL90 |
| B | ALA91 |
| B | SER115 |
| B | ILE116 |
| B | PHE165 |
| B | LEU166 |
| B | ARG208 |
| B | ALA209 |
| B | PRO233 |
| B | HIS234 |
| B | ILE235 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01084","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"18391406","evidenceCode":"ECO:0000305"},{"source":"Reference","evidenceCode":"ECO:0000305","citation":{"citationType":"submission","publicationDate":"FEB-2009","submissionDatabase":"PDB data bank","title":"Crystal structure of diphthine synthase from Pyrococcus horikoshii OT3.","authoringGroup":["RIKEN structural genomics initiative (RSGI)"]}}]} |
| Chain | Residue | Details |
