2P2T

Crystal structure of dynein light chain LC8 bound to residues 123-138 of intermediate chain IC74

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000132	biological_process	establishment of mitotic spindle orientation
A	0003714	molecular_function	transcription corepressor activity
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005814	cellular_component	centriole
A	0005829	cellular_component	cytosol
A	0005856	cellular_component	cytoskeleton
A	0005868	cellular_component	cytoplasmic dynein complex
A	0005874	cellular_component	microtubule
A	0005875	cellular_component	microtubule associated complex
A	0007017	biological_process	microtubule-based process
A	0007283	biological_process	spermatogenesis
A	0007290	biological_process	spermatid nucleus elongation
A	0007291	biological_process	sperm individualization
A	0007476	biological_process	imaginal disc-derived wing morphogenesis
A	0008407	biological_process	chaeta morphogenesis
A	0015630	cellular_component	microtubule cytoskeleton
A	0022416	biological_process	chaeta development
A	0030286	cellular_component	dynein complex
A	0032991	cellular_component	protein-containing complex
A	0034454	biological_process	microtubule anchoring at centrosome
A	0035220	biological_process	wing disc development
A	0042803	molecular_function	protein homodimerization activity
A	0045505	molecular_function	dynein intermediate chain binding
A	0045892	biological_process	negative regulation of DNA-templated transcription
A	0048477	biological_process	oogenesis
A	0051017	biological_process	actin filament bundle assembly
A	0051959	molecular_function	dynein light intermediate chain binding
A	0090571	cellular_component	RNA polymerase II transcription repressor complex
A	0097718	molecular_function	disordered domain specific binding
A	0141006	biological_process	piRNA-mediated retrotransposon silencing by heterochromatin formation
A	1904801	biological_process	positive regulation of neuron remodeling

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ACT A 91

Chain	Residue
A	GLU15
A	ARG71
A	HOH137

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site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NA A 101

Chain	Residue
A	GLU45
A	LYS48

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Functional Information from PROSITE/UniProt

site_id	PS01239
Number of Residues	15
Details	DYNEIN_LIGHT_1 Dynein light chain type 1 signature. HcIvGRnFGSyVTHE

Chain	Residue	Details
A	HIS55-GLU69

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