2P28
Structure of the PHE2 and PHE3 fragments of the integrin beta2 subunit
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0007155 | biological_process | cell adhesion |
| A | 0007160 | biological_process | cell-matrix adhesion |
| A | 0007229 | biological_process | integrin-mediated signaling pathway |
| A | 0008305 | cellular_component | integrin complex |
| A | 0038023 | molecular_function | signaling receptor activity |
| B | 0007155 | biological_process | cell adhesion |
| B | 0007160 | biological_process | cell-matrix adhesion |
| B | 0007229 | biological_process | integrin-mediated signaling pathway |
| B | 0008305 | cellular_component | integrin complex |
| B | 0038023 | molecular_function | signaling receptor activity |
Functional Information from PROSITE/UniProt
| site_id | PS00022 |
| Number of Residues | 12 |
| Details | EGF_1 EGF-like domain signature 1. CrCdtGyiGKnC |
| Chain | Residue | Details |
| B | CYS448-CYS459 | |
| B | CYS540-CYS551 |
| site_id | PS00243 |
| Number of Residues | 14 |
| Details | I_EGF_1 Integrins beta chain EGF (I-EGF) domain signature. CsGl..GdCvCgqClC |
| Chain | Residue | Details |
| B | CYS484-CYS497 | |
| B | CYS527-CYS542 |
| site_id | PS01186 |
| Number of Residues | 14 |
| Details | EGF_2 EGF-like domain signature 2. CrCdtGYigknce..C |
| Chain | Residue | Details |
| B | CYS448-CYS461 | |
| B | CYS540-CYS551 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 50 |
| Details | Domain: {"description":"PSI","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Pyrrolidone carboxylic acid","evidences":[{"source":"PubMed","id":"2954816","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19349973","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19349973","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20033057","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24385486","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4NEH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NEN","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 38 |
| Details | Domain: {"description":"I-EGF 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU01392","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Motif: {"description":"Cell attachment site","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
