Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004402 | molecular_function | histone acetyltransferase activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0006325 | biological_process | chromatin organization |
| A | 0031509 | biological_process | subtelomeric heterochromatin formation |
| A | 0042393 | molecular_function | histone binding |
| B | 0004402 | molecular_function | histone acetyltransferase activity |
| B | 0005634 | cellular_component | nucleus |
| B | 0006325 | biological_process | chromatin organization |
| B | 0031509 | biological_process | subtelomeric heterochromatin formation |
| B | 0042393 | molecular_function | histone binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT A 805 |
| Chain | Residue |
| A | PHE247 |
| A | HOH932 |
| A | HOH1059 |
| A | HOH1139 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 806 |
| Chain | Residue |
| A | ALA275 |
| A | ARG286 |
| A | HIS327 |
| A | HOH1023 |
| A | HOH1170 |
| site_id | AC3 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE ACO A 401 |
| Chain | Residue |
| A | PHE185 |
| A | SER239 |
| A | MET241 |
| A | LEU242 |
| A | ILE243 |
| A | GLN248 |
| A | GLY249 |
| A | GLN250 |
| A | GLY251 |
| A | HIS252 |
| A | GLY253 |
| A | ALA254 |
| A | PRO278 |
| A | SER279 |
| A | SER281 |
| A | TYR282 |
| A | LYS284 |
| A | LEU285 |
| A | PHE288 |
| A | HOH828 |
| A | HOH900 |
| A | HOH930 |
| A | HOH1152 |
| A | HOH1173 |
| A | HOH1181 |
| site_id | AC4 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE ACO B 401 |
| Chain | Residue |
| B | PHE185 |
| B | SER239 |
| B | MET241 |
| B | LEU242 |
| B | ILE243 |
| B | GLN248 |
| B | GLY249 |
| B | GLN250 |
| B | GLY251 |
| B | GLY253 |
| B | ALA254 |
| B | PRO278 |
| B | SER279 |
| B | SER281 |
| B | TYR282 |
| B | LYS284 |
| B | LEU285 |
| B | HOH842 |
| B | HOH969 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACM A 801 |
| Chain | Residue |
| A | GLU97 |
| A | ASN98 |
| A | CYS101 |
| A | HOH1127 |
| B | TYR162 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACM B 802 |
| Chain | Residue |
| A | ASN156 |
| A | ASN209 |
| B | GLY18 |
| B | ASP100 |
| B | CYS101 |
| B | HOH819 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACM A 803 |
| Chain | Residue |
| A | GLY140 |
| A | CYS168 |
| A | HOH1093 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACM B 804 |
| Chain | Residue |
| B | GLU24 |
| B | LYS26 |
| B | CYS27 |
| B | TYR69 |
| B | LYS70 |
| B | GLY71 |
| B | LEU72 |
Functional Information from PROSITE/UniProt
| site_id | PS00047 |
| Number of Residues | 5 |
| Details | HISTONE_H4 Histone H4 signature. GAKRH |
| Chain | Residue | Details |
| P | GLY14-HIS18 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Region: {"description":"Interaction with histone H4 N-terminus","evidences":[{"source":"PubMed","id":"22615379","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Region: {"description":"Interaction with histone H4 N-terminus","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"PubMed","id":"22615379","evidenceCode":"ECO:0000303"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"22615379","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Site: {"description":"Interaction with histone H4 N-terminus","evidences":[{"source":"PubMed","id":"22615379","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine; by AMPK","evidences":[{"source":"PubMed","id":"28143904","evidenceCode":"ECO:0000269"}]} |
