2OZP
Crystal structure of N-acetyl-gamma-glutamyl-phosphate reductase (TTHA1904) from Thermus thermophilus
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003942 | molecular_function | N-acetyl-gamma-glutamyl-phosphate reductase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006526 | biological_process | L-arginine biosynthetic process |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009085 | biological_process | lysine biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| A | 0019878 | biological_process | lysine biosynthetic process via aminoadipic acid |
| A | 0043870 | molecular_function | N-acetyl-gamma-aminoadipyl-phosphate reductase activity |
| A | 0051287 | molecular_function | NAD binding |
| A | 0070401 | molecular_function | NADP+ binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1001 |
| Chain | Residue |
| A | HIS78 |
| A | ARG103 |
| A | GLY148 |
| A | CYS149 |
| A | ARG209 |
| A | HIS210 |
| A | HOH1021 |
| A | HOH1274 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1002 |
| Chain | Residue |
| A | SER37 |
| A | ARG38 |
| A | ARG39 |
| A | SER13 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE AZI A 1003 |
| Chain | Residue |
| A | ARG135 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE AZI A 1004 |
| Chain | Residue |
| A | GLY14 |
| A | TYR15 |
| A | ALA16 |
| A | GLY184 |
| A | ALA185 |
| A | HOH1059 |
| A | HOH1080 |
| A | HOH1134 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE AZI A 1005 |
| Chain | Residue |
| A | ARG112 |
| A | TYR113 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE AZI A 1006 |
| Chain | Residue |
| A | ARG125 |
| A | HOH1102 |
| A | HOH1159 |
| A | HOH1304 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE AZI A 1007 |
| Chain | Residue |
| A | ARG209 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE AZI A 1008 |
| Chain | Residue |
| A | HIS46 |
| A | ARG53 |
| A | LYS272 |
| A | GLN273 |
Functional Information from PROSITE/UniProt
| site_id | PS01224 |
| Number of Residues | 17 |
| Details | ARGC N-acetyl-gamma-glutamyl-phosphate reductase active site. IAgAGCNATAtllGLyP |
| Chain | Residue | Details |
| A | ILE144-PRO160 |
