2OYH
Crystal Structure of Fragment D of gammaD298,301A Fibrinogen with the Peptide Ligand Gly-His-Arg-Pro-Amide
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005102 | molecular_function | signaling receptor binding |
| A | 0005577 | cellular_component | fibrinogen complex |
| A | 0007596 | biological_process | blood coagulation |
| A | 0030168 | biological_process | platelet activation |
| A | 0051258 | biological_process | protein polymerization |
| B | 0005102 | molecular_function | signaling receptor binding |
| B | 0005577 | cellular_component | fibrinogen complex |
| B | 0007596 | biological_process | blood coagulation |
| B | 0030168 | biological_process | platelet activation |
| B | 0051258 | biological_process | protein polymerization |
| C | 0005102 | molecular_function | signaling receptor binding |
| C | 0005577 | cellular_component | fibrinogen complex |
| C | 0007596 | biological_process | blood coagulation |
| C | 0030168 | biological_process | platelet activation |
| C | 0051258 | biological_process | protein polymerization |
| D | 0005102 | molecular_function | signaling receptor binding |
| D | 0005577 | cellular_component | fibrinogen complex |
| D | 0007596 | biological_process | blood coagulation |
| D | 0030168 | biological_process | platelet activation |
| D | 0051258 | biological_process | protein polymerization |
| E | 0005102 | molecular_function | signaling receptor binding |
| E | 0005577 | cellular_component | fibrinogen complex |
| E | 0007596 | biological_process | blood coagulation |
| E | 0030168 | biological_process | platelet activation |
| E | 0051258 | biological_process | protein polymerization |
| F | 0005102 | molecular_function | signaling receptor binding |
| F | 0005577 | cellular_component | fibrinogen complex |
| F | 0007596 | biological_process | blood coagulation |
| F | 0030168 | biological_process | platelet activation |
| F | 0051258 | biological_process | protein polymerization |
Functional Information from PROSITE/UniProt
| site_id | PS00514 |
| Number of Residues | 13 |
| Details | FIBRINOGEN_C_1 Fibrinogen C-terminal domain signature. WWYnrChaAnpNG |
| Chain | Residue | Details |
| B | TRP402-GLY414 | |
| C | TRP334-GLY346 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:10074346, ECO:0000269|PubMed:19296670, ECO:0000269|PubMed:9016719, ECO:0000269|PubMed:9207064, ECO:0000269|PubMed:9333233, ECO:0000269|PubMed:9628725, ECO:0007744|PDB:1FID |
| Chain | Residue | Details |
| C | ASP318 | |
| C | ASP320 | |
| C | PHE322 | |
| C | GLY324 | |
| F | ASP318 | |
| F | ASP320 | |
| F | PHE322 | |
| F | GLY324 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine; in variant Asahi |
| Chain | Residue | Details |
| C | ASN308 | |
| F | ASN308 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | CROSSLNK: Isoglutamyl lysine isopeptide (Gln-Lys) (interchain with K-432) |
| Chain | Residue | Details |
| C | GLN398 | |
| F | GLN398 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | CROSSLNK: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-424) |
| Chain | Residue | Details |
| C | LYS406 | |
| F | LYS406 |
