2OYE
Indomethacin-(R)-alpha-ethyl-ethanolamide bound to Cyclooxygenase-1
Functional Information from GO Data
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 36 |
| Details | TRANSMEM: Helical |
| Chain | Residue | Details |
| P | ILE74-LEU82 | |
| P | PRO86-LEU92 | |
| P | ARG97-ALA105 | |
| P | ILE108-ASN122 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton acceptor |
| Chain | Residue | Details |
| P | HIS207 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | ACT_SITE: For cyclooxygenase activity => ECO:0000269|PubMed:2122967 |
| Chain | Residue | Details |
| P | TYR385 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | BINDING: axial binding residue |
| Chain | Residue | Details |
| P | HIS388 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | SITE: Not glycosylated => ECO:0000269|PubMed:8349699 |
| Chain | Residue | Details |
| P | ASN104 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | SITE: Aspirin-acetylated serine |
| Chain | Residue | Details |
| P | SER530 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:8349699 |
| Chain | Residue | Details |
| P | ASN68 | |
| P | ASN144 | |
| P | ASN410 |
