2OX1

Archaeal Dehydroquinase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003855	molecular_function	3-dehydroquinate dehydratase activity
A	0008652	biological_process	amino acid biosynthetic process
A	0009073	biological_process	aromatic amino acid family biosynthetic process
A	0009423	biological_process	chorismate biosynthetic process
A	0016829	molecular_function	lyase activity
A	0046279	biological_process	3,4-dihydroxybenzoate biosynthetic process
B	0003855	molecular_function	3-dehydroquinate dehydratase activity
B	0008652	biological_process	amino acid biosynthetic process
B	0009073	biological_process	aromatic amino acid family biosynthetic process
B	0009423	biological_process	chorismate biosynthetic process
B	0016829	molecular_function	lyase activity
B	0046279	biological_process	3,4-dihydroxybenzoate biosynthetic process
C	0003855	molecular_function	3-dehydroquinate dehydratase activity
C	0008652	biological_process	amino acid biosynthetic process
C	0009073	biological_process	aromatic amino acid family biosynthetic process
C	0009423	biological_process	chorismate biosynthetic process
C	0016829	molecular_function	lyase activity
C	0046279	biological_process	3,4-dihydroxybenzoate biosynthetic process
D	0003855	molecular_function	3-dehydroquinate dehydratase activity
D	0008652	biological_process	amino acid biosynthetic process
D	0009073	biological_process	aromatic amino acid family biosynthetic process
D	0009423	biological_process	chorismate biosynthetic process
D	0016829	molecular_function	lyase activity
D	0046279	biological_process	3,4-dihydroxybenzoate biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 201

Chain	Residue
A	ARG45
A	HIS98
A	LYS122
A	ARG159
A	GLN182

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL B 202

Chain	Residue
B	LYS122
B	THR6
B	GLU23
B	ARG25
B	HIS98

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL C 203

Chain	Residue
C	GLU23
C	ARG45
C	HIS98
C	LYS122
C	PHE149

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL D 204

Chain	Residue
D	HIS98
D	LYS122
D	PHE149
D	ARG159
D	GLN182

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Proton donor/acceptor => ECO:0000255|HAMAP-Rule:MF_00214

Chain	Residue	Details
A	HIS98
B	HIS98
C	HIS98
D	HIS98

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	ACT_SITE: Schiff-base intermediate with substrate => ECO:0000255|HAMAP-Rule:MF_00214

Chain	Residue	Details
A	LYS122
B	LYS122
C	LYS122
D	LYS122

---

site_id	SWS_FT_FI3
Number of Residues	16
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00214

Chain	Residue	Details
A	GLU23
C	ARG45
C	ARG159
C	GLN182
D	GLU23
D	ARG45
D	ARG159
D	GLN182
A	ARG45
A	ARG159
A	GLN182
B	GLU23
B	ARG45
B	ARG159
B	GLN182
C	GLU23

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