Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004222 | molecular_function | metalloendopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008237 | molecular_function | metallopeptidase activity |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0031012 | cellular_component | extracellular matrix |
| B | 0004222 | molecular_function | metalloendopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008237 | molecular_function | metallopeptidase activity |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0031012 | cellular_component | extracellular matrix |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 444 |
| Chain | Residue |
| A | HIS401 |
| A | HIS405 |
| A | HIS411 |
| A | 8MR501 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 445 |
| Chain | Residue |
| A | HIS175 |
| A | ASP177 |
| A | HIS190 |
| A | HIS203 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 444 |
| Chain | Residue |
| B | HIS405 |
| B | HIS411 |
| B | 8MR502 |
| B | HIS401 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 445 |
| Chain | Residue |
| B | HIS175 |
| B | ASP177 |
| B | HIS190 |
| B | HIS203 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 446 |
| Chain | Residue |
| A | ASP182 |
| A | GLY183 |
| A | ASP185 |
| A | LEU187 |
| A | ASP205 |
| A | GLU208 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA A 447 |
| Chain | Residue |
| A | ASP131 |
| A | ASP206 |
| A | GLU208 |
| A | HOH519 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 446 |
| Chain | Residue |
| B | ASP182 |
| B | GLY183 |
| B | ASP185 |
| B | LEU187 |
| B | ASP205 |
| B | GLU208 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE CA B 447 |
| Chain | Residue |
| A | LEU212 |
| B | SER211 |
| B | LEU212 |
| B | GLY213 |
| B | LYS214 |
| B | GLY215 |
| B | GLN391 |
| B | HOH534 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE CA A 448 |
| Chain | Residue |
| A | SER211 |
| A | LEU212 |
| A | LYS214 |
| A | GLY215 |
| A | GLN391 |
| A | HOH503 |
| A | HOH567 |
| B | LEU212 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CA B 448 |
| Chain | Residue |
| B | ASP131 |
| B | ASP206 |
| B | GLU208 |
| site_id | BC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 449 |
| Chain | Residue |
| A | GLY213 |
| A | SER394 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 450 |
| Chain | Residue |
| A | ASN127 |
| A | TYR128 |
| B | ASN127 |
| B | TYR128 |
| site_id | BC4 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE 8MR A 501 |
| Chain | Residue |
| A | LEU187 |
| A | LEU188 |
| A | ALA189 |
| A | HIS190 |
| A | VAL398 |
| A | HIS401 |
| A | GLN402 |
| A | HIS405 |
| A | HIS411 |
| A | TYR420 |
| A | PRO421 |
| A | TYR423 |
| A | ZN444 |
| A | HOH557 |
| site_id | BC5 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE 8MR B 502 |
| Chain | Residue |
| B | LEU187 |
| B | LEU188 |
| B | ALA189 |
| B | HIS401 |
| B | GLN402 |
| B | HIS405 |
| B | HIS411 |
| B | PRO421 |
| B | MET422 |
| B | TYR423 |
| B | ZN444 |
| B | HOH547 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | GLN402 | |
| B | GLN402 | |
| Chain | Residue | Details |
| A | ASP131 | |
| A | ASP205 | |
| A | ASP206 | |
| A | GLU208 | |
| B | ASP131 | |
| B | ASP165 | |
| B | ASP182 | |
| B | GLY183 | |
| B | ASP185 | |
| B | LEU187 | |
| B | GLY197 | |
| A | ASP165 | |
| B | GLN199 | |
| B | ASP201 | |
| B | ASP205 | |
| B | ASP206 | |
| B | GLU208 | |
| A | ASP182 | |
| A | GLY183 | |
| A | ASP185 | |
| A | LEU187 | |
| A | GLY197 | |
| A | GLN199 | |
| A | ASP201 | |
| Chain | Residue | Details |
| A | HIS175 | |
| B | HIS190 | |
| B | HIS203 | |
| B | HIS401 | |
| B | HIS405 | |
| B | HIS411 | |
| A | ASP177 | |
| A | HIS190 | |
| A | HIS203 | |
| A | HIS401 | |
| A | HIS405 | |
| A | HIS411 | |
| B | HIS175 | |
| B | ASP177 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN120 | |
| A | ASN127 | |
| B | ASN120 | |
| B | ASN127 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1hfs |
| Chain | Residue | Details |
| A | MET419 | |
| A | GLN402 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1hfs |
| Chain | Residue | Details |
| B | MET419 | |
| B | GLN402 | |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1hfs |
| Chain | Residue | Details |
| A | GLN402 | |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1hfs |
| Chain | Residue | Details |
| B | GLN402 | |
