Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004222 | molecular_function | metalloendopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008237 | molecular_function | metallopeptidase activity |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0031012 | cellular_component | extracellular matrix |
| B | 0004222 | molecular_function | metalloendopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008237 | molecular_function | metallopeptidase activity |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0031012 | cellular_component | extracellular matrix |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 444 |
| Chain | Residue |
| A | HIS401 |
| A | HIS405 |
| A | HIS411 |
| A | 6MR501 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 445 |
| Chain | Residue |
| A | HIS175 |
| A | ASP177 |
| A | HIS190 |
| A | HIS203 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 444 |
| Chain | Residue |
| B | HIS405 |
| B | HIS411 |
| B | 6MR502 |
| B | HIS401 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 445 |
| Chain | Residue |
| B | HIS175 |
| B | ASP177 |
| B | HIS190 |
| B | HIS203 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 446 |
| Chain | Residue |
| A | ASP165 |
| A | GLY197 |
| A | GLN199 |
| A | ASP201 |
| A | HOH564 |
| A | HOH583 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 447 |
| Chain | Residue |
| A | ASP182 |
| A | GLY183 |
| A | ASP185 |
| A | LEU187 |
| A | ASP205 |
| A | GLU208 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CA A 448 |
| Chain | Residue |
| A | ASP131 |
| A | ASP206 |
| A | GLU208 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA A 449 |
| Chain | Residue |
| A | SER149 |
| A | THR152 |
| A | HOH528 |
| A | HOH535 |
| A | HOH547 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 446 |
| Chain | Residue |
| B | ASP165 |
| B | GLY197 |
| B | GLN199 |
| B | ASP201 |
| B | HOH505 |
| B | HOH540 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 447 |
| Chain | Residue |
| B | ASP182 |
| B | GLY183 |
| B | ASP185 |
| B | LEU187 |
| B | ASP205 |
| B | GLU208 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CA B 448 |
| Chain | Residue |
| B | ASP131 |
| B | ASP206 |
| B | GLU208 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 449 |
| Chain | Residue |
| B | SER149 |
| B | THR152 |
| B | HOH528 |
| B | HOH551 |
| B | HOH552 |
| B | HOH593 |
| site_id | BC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 450 |
| Chain | Residue |
| A | GLY213 |
| A | SER394 |
| site_id | BC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 450 |
| Chain | Residue |
| B | GLY213 |
| B | SER394 |
| site_id | BC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 451 |
| Chain | Residue |
| A | HOH527 |
| B | ARG143 |
| B | PHE396 |
| site_id | BC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 451 |
| Chain | Residue |
| A | ARG143 |
| A | HOH565 |
| site_id | BC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 452 |
| Chain | Residue |
| A | PRO430 |
| A | LEU431 |
| A | HOH524 |
| A | HOH529 |
| A | HOH610 |
| site_id | BC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 453 |
| Chain | Residue |
| A | ASN127 |
| A | TYR128 |
| B | ASN127 |
| B | TYR128 |
| site_id | CC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE 6MR A 501 |
| Chain | Residue |
| A | LEU188 |
| A | ALA189 |
| A | HIS401 |
| A | GLN402 |
| A | HIS405 |
| A | HIS411 |
| A | LEU418 |
| A | TYR420 |
| A | PRO421 |
| A | MET422 |
| A | TYR423 |
| A | ZN444 |
| A | HOH503 |
| A | HOH608 |
| site_id | CC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE 6MR B 502 |
| Chain | Residue |
| B | TYR423 |
| B | ZN444 |
| B | HOH545 |
| B | LEU188 |
| B | ALA189 |
| B | HIS401 |
| B | GLN402 |
| B | HIS405 |
| B | HIS411 |
| B | LEU418 |
| B | TYR420 |
| B | PRO421 |
| B | MET422 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"12051944","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 24 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12051944","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12051944","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12077439","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1hfs |
| Chain | Residue | Details |
| A | MET419 | |
| A | GLN402 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1hfs |
| Chain | Residue | Details |
| B | MET419 | |
| B | GLN402 | |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1hfs |
| Chain | Residue | Details |
| A | GLN402 | |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1hfs |
| Chain | Residue | Details |
| B | GLN402 | |
